LY-367385 hydrochloride
CAS 198419-91-9 MFCD02262124
化学结构图
SMILES: CC1=CC(=CC=C1[C@H](N)C(O)=O)C(O)=O
化学属性
| Mol. Formula | C10H11NO4·HCl |
|---|---|
| Mol. Weight | 245.66 |
别名和识别编码
| Chemical Name | LY-367385 hydrochloride |
|---|---|
| Synonym | (S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid LY-367385 hydrochloride |
| MDL Number | MFCD02262124 |
| PubChem Substance ID | 329817409 |
| CAS Number | 198419-91-9 (free base) |
| Chemical Name Translation |
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分类
- {SNA} Approved Therapeutics/Drug Candidates,
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Eli Lilly, Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, L,
相关文献及参考
- [2]. Bruno V, et al. Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors. Neuropharmacology. 1999 Feb;38(2):199-207.
- [3]. Chapman AG, et al. Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid). Eur J Pharmacol. 1999 Feb 26;368(1):17-24.
- [1]. Clark et al. (+)-2-Methyl-4-carboxyphenylglycine (LY 367385) selectively antagonises metabotropic glutamate mGluR1 receptors. Bioorg.Med.Chem.Lett. November 1997, 7 (21): 2777-2780.
- [1]. Clark et al. (+)-2-Methyl-4-carboxyphenylglycine (LY 367385) selectively antagonises metabotropic glutamate mGluR1 receptors. Bioorg.Med.Chem.Lett. November 1997, 7 (21): 2777-2780.
- [2]. Bruno V, et al. Neuroprotective activity of the potent and se
