3(2H)-Pyridazinone,4,5-dihydro-6-(4-(4-pyridinylamino)phenyl)-
CAS 98326-32-0 MFCD01758407
化学结构图
SMILES: O=C1CCC(=NN1)C1=CC=C(C=C1)NC1=CC=NC=C1
化学属性
| Mol. Formula | C15H14N4O |
|---|---|
| Mol. Weight | 266.33 |
别名和识别编码
| Chemical Name | 3(2H)-Pyridazinone,4,5-dihydro-6-(4-(4-pyridinylamino)phenyl)- |
|---|---|
| Synonym | 6-(4-(4-Pyridinylamino)phenyl)-4,5-dihydro-3(2H)-pyridazinone |
| CAS Number | 98326-32-0 |
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相关文献及参考
- [2]. Erhardt L. An emerging role for calcium sensitisation in the treatment of heart failure. Expert Opin Investig Drugs. 2005 Jun;14(6):659-70.
- [1]. Lehtonen LA, et al. Pharmacokinetics and pharmacodynamics of intravenous inotropic agents. Clin Pharmacokinet. 2004;43(3):187-203.
- [1]. Lehtonen LA, et al. Pharmacokinetics and pharmacodynamics of intravenous inotropic agents. Clin Pharmacokinet. 2004;43(3):187-203.
- [2]. Erhardt L. An emerging role for calcium sensitisation in the treatment of heart failure. Expert Opin Investig Drugs. 2005 Jun;14(6):659-70.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 341 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0145019
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 97 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0145019
