(3S, 4S, 5R, 6R)-6-(ACETYLAMINO)-4,5-DIHYDROXY-3-PIPERIDINECARBOXYLIC ACID
CAS 54795-58-3 MFCD01631253
化学结构图
SMILES: CC(=O)N[C@H]1NC[C@@H]([C@H](O)[C@@H]1O)C(O)=O
化学属性
| Mol. Formula | C8H14N2O5 |
|---|---|
| Mol. Weight | 218.21 |
别名和识别编码
| Chemical Name | Siastatin B |
|---|---|
| Synonym | (3S, 4S, 5R, 6R)-6-(Acetylamino)-4,5-dihydroxy-3-piperidinecarboxylic acid Siastatin B |
| MDL Number | MFCD01631253 |
| PubChem Substance ID | 24899775 |
| CAS Number | 54795-58-3 |
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分类
- {SNA} Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Inhibitors, Inhibitors and Substrates, L to O, Neuraminidase, 分子生物学, 生化试剂, 糖生物学, 翻译后修饰, 蛋白质组学, 酶、抑制剂和底物
- {SA} Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Glycobiology, Inhibitors, Inhibitors and Substrates, L to O, Neuraminidase, Post-Translational Modification, Proteomics
- {SNA} Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, In
相关文献及参考
- 1. Umezawa, T., et al., Purification and characterization of a sialidase inhibitor, siastatin, produced by Streptomyces J. Antibiot. 27 , 963-969, (1974) 摘要
- Knapp, S. , Zhao, D. Org. Lett. 2 , 4037, (2000) 摘要
安全信息
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
GHS Symbol
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >125 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 27,963,1974
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
