4-氨基吲哚 4-氨基吲哚

CAS 5192-23-4 MFCD01076559

化学结构图

5192-23-4
SMILES: Nc1cccc2[nH]ccc12

化学属性

Mol. FormulaC8H8N2
Mol. Weight132.16
Melting Point106-109°C
Density1.268
TSCANo
Solubility不溶
Stability对空气敏感
Appearance 暗紫色粉末。
Boiling Point354.0±15.0 °C at 760 mmHg

别名和识别编码

Chemical Name4-氨基吲哚
CAS Number5192-23-4
Alfabeta NameAMINOINDOLE H41---
MDL NumberMFCD01076559
Synonym 4-Aminoindole {LY} 4-Aminoindole {} {LY} 4-Aminoindole {} {} {LY} 4-Aminoindole {} {} {} {LY} 4-Aminoindole {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Aminoindole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
EC Number000-000-0
Beilstein Registry Number22(4)4296
PubChem Substance ID583431
Reaxys-RN114919
Chemical Name Translation4-氨基吲哚
LabNetwork Molecule IDLN00173069
InChIInChI=1S/C8H8N2/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5,10H,9H2
Canonical SMILESNC1=CC=CC2=C1C=CN2
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Building Blocks, C7 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Indoles
  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; 1fragment

产品应用

  • Reactant for preparation of:
  • ? Inhibitors of bacterial thymidylate synthase
  • ? Mimetics of non-alkaloid toxin lignan anticancer and antiviral agent Podophyllotoxin (PPT)
  • ? Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
  • ? Protein kinase C θ (PKCθ) inhibitors
  • ? Indolic non-peptidic HIV protease inhibitors
  • ? Transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
  • ? Cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors
  • ? 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitors
  • ? Short chain 4-substituted indoles as potent αvβ3 antagonist
  • ? Ligands of serotonin transporter and 5-HT1A receptors

相关文献及参考

  • Short: III/35C2
  • Beilstein:22(4)4296

安全信息

Warnings AIR SENSITIVE, IRRITANT-HARMFUL, KEEP COLD
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P301+P317
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Codes Xi
Packing GroupIII

其他信息

  • MSDS 信息:4-Aminoindole(5192-23-4).msds
  • MOL 文件:5192-23-4.mol
  • Sigma Aldrich:5192-23-4(sigmaaldrich)
  • Alfa Aesar:4-氨基吲哚,98% 4-Aminoindole, 98%(5192-23-4)
  • 敏感性:Air Sensitive
  • 4-氨基吲哚价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 A2070 4-氨基吲哚 4-Aminoindole 1G 1720元 2014/06/02 A2070 4-氨基吲哚 4-Aminoindole 5G 6000元 2010/06/21 368611000 4-氨基吲哚 4-Aminoindole 97% 100 MG 485元
  • 图谱信息:4-氨基吲哚(5192-23-4)红外图谱(IR2) 4-氨基吲哚(5192-23-4)红外图谱(IR1)
  • F:8-10-34
  • 检测方法:HPLC
  • Acros Organics:4-氨基吲哚 4-Aminoindole, 97%(5192-23-4)
  • 用途二:精细化工原料,医药中间体。
  • 用途一:在有机合成上利用其氨基的活泼性合成各种化合物

系列性分类


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