1-Phenyl-1H-1,2,4-Triazole 1-苯基-1H-1,2,4-三氮唑

CAS 13423-60-4 MFCD01076193

化学结构图

13423-60-4
SMILES: C1=NN(C=N1)C1C=CC=CC=1

化学属性

Mol. FormulaC8H7N3
Mol. Weight145.18

别名和识别编码

Chemical Name1-Phenyl-1H-1,2,4-Triazole
Synonym 1-Phenyl-1H-1,2,4-triazole
Wiswesser Line NotationT5NN DNJ AR
CAS Number13423-60-4
Beilstein Registry Number0116495
Chemical Name Translation1-苯基-1H-1,2,4-三氮唑
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安全信息

RTECSXZ5075000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 155 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 47,778,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 674 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 121,443,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 261 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 47,778,1958

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