Tezosentan
CAS 180384-57-0 MFCD00949625
化学结构图
SMILES: COC1C=CC=CC=1OC1C(=NC(=NC=1NS(=O)(=O)C1C=CC(=CN=1)C(C)C)C1C=C(N=CC=1)C1NN=NN=1)OCCO
化学属性
| Mol. Formula | C27H27N9O6S |
|---|---|
| Mol. Weight | 605.62 |
别名和识别编码
| Chemical Name | Tezosentan |
|---|---|
| CAS Number | 180384-57-0 |
| Synonym | N-[6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-(1-methylethyl)-2-pyridinesulfonamide |
| Chemical Name Translation |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Aromatics
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
产品应用
- A potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan (B675900).
相关文献及参考
- Clozel, M., et al.: J. Pharmacol. Exp. Ther., 290, 840 (1999),
- Dingemanse, J., et al.: Br. J. Clin. Pharmacol., 53, 355 (2002),
- Schalcher, C., et al.: Am. Heart J., 142, 340 (2001),
- [1]. Clozel M, et al. Pharmacology of tezosentan, new endothelin receptor antagonist designed for parenteral use. J Pharmacol Exp Ther. 1999 Aug;290(2):840-6.
