Nu1025 2-甲基-8-羟基-4-喹唑啉酮
CAS 90417-38-2 MFCD00942555
化学结构图
SMILES: CC1NC(=O)C2C=CC=C(O)C=2N=1
化学属性
| Mol. Formula | C9H8N2O2 |
|---|---|
| Mol. Weight | 176.17 |
| Density | 1.422 |
| Melting Point | 253-258 |
别名和识别编码
| Chemical Name | Nu1025 |
|---|---|
| CAS Number | 90417-38-2 |
| Synonym | 8-Hydroxy-2-methylquinazolin-4[3H]-one NSC 696807 NU-1025 |
| MDL Number | MFCD00942555 |
| EC Number | 250-023-7 |
| Beilstein Registry Number | 2384789 |
| PubChem Substance ID | 24724555 |
| Chemical Name Translation | 2-甲基-8-羟基-4-喹唑啉酮 |
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资金保障
专业采购外包团队在线服务
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现货库存
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分类
- Aromatics
- {SNA} Bioactive Small Molecule Alphabetical Index, Cyclin-Dependent Kinase (CDK), Kinase/Phosphatase Biology, N, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclin-Dependent Kinase (CDK), Kinase/Phosphatase Biology, N, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
- Inhibitors
产品应用
- A potent inhibitor of poly (ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.
相关文献及参考
- Griffin, R.J., et al.: J. Med. Chem., 41, 5247 (1998),
- De Soto, J., et al.: Int. J. Biol. Sci., 2, 179 (2006),
安全信息
GHS Symbol
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
