(E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-Tetrahydro-2,3'-Bipyridine Dihydrochloride (E)-3-(2,4-二甲氧基苯基)亚甲基)-3,4,5,6-四氢-2,3'-联吡啶二盐酸盐
CAS 156223-05-1 MFCD00941364
化学结构图
SMILES:
化学属性
| Mol. Weight | 381.30 |
|---|---|
| Mol. Formula | C19H20N2O2· 2HCl |
别名和识别编码
| Synonym | GTS-21 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride DMBX-anabaseine DMXB-A DMXB GTS21 |
|---|---|
| Chemical Name | (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-Tetrahydro-2,3'-Bipyridine Dihydrochloride |
| MDL Number | MFCD00941364 |
| Chemical Name Translation | (E)-3-(2,4-二甲氧基苯基)亚甲基)-3,4,5,6-四氢-2,3'-联吡啶二盐酸盐 |
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分类
- {SNA} Agonists, Cell Biology, Cell Signaling and Neuroscience, Cholinergics, Ion Channels, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, Nicotinic Acetylcholine Receptor Modulators
- {SNA} Agonists, Bioactive Small Molecule Alphabetical Index, Cholinergics, G, Ion Channels, Ligand-Gated Ion Channels, Neuroscience, Neurotransmission, Neurotransmitters, Nicotinic Acetylcholine Receptor Modulators, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- [2]. Zhang R, et al. N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine. J Pharmacol Exp Ther. 2006;317(3):1276-1284.
- [3]. Mei Z, et al. α7 nAchR agonist GTS 21 reduces radiation induced lung injury. Oncol Rep. 2018;40(4):2287-2297.
- [1]. Briggs CA, et al. Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo. Pharmacol Biochem Behav. 1997;57(1-2):231-241.
- [1]. Briggs CA, et al. Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo. Pharmacol Biochem Behav. 1997;57(1-2):231-241.
- [2]. Zhang R, et al. N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine. J Pharmacol Exp Ther. 2006;317(3):1276-1284.
- [3]. Mei Z
