SB 200646 HYDROCHLORIDE 1-(1-甲基-1H-吲哚-5-基)-3-(吡啶-3-基)脲盐酸盐
CAS 143797-62-0 MFCD00913519
化学结构图
SMILES: Cl.CN1C=CC2=CC(=CC=C12)NC(=O)NC1C=NC=CC=1
化学属性
| Mol. Formula | C15H14N4O.ClH |
|---|---|
| Mol. Weight | 311.77 |
别名和识别编码
| Chemical Name | SB 200646 HYDROCHLORIDE |
|---|---|
| Synonym | N-(1-Methyl-1H-5-indolyl)-N′-(3-pyridinyl)urea hydrochloride |
| MDL Number | MFCD00913519 |
| PubChem Substance ID | 24278805 |
| Chemical Name Translation | 1-(1-甲基-1H-吲哚-5-基)-3-(吡啶-3-基)脲盐酸盐 |
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分类
- {SNA} Antagonists, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Neuroscience, Neurotransmission, Neurotransmitters, P to Q, Protein Kinase p38 MAPK, Serotonergics
相关文献及参考
- [2]. Kennett GA, et al. In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist. Br J Pharmacol. 1994 Mar;111(3):797-802.
- [3]. Theile JW, et al. Role of 5-hydroxytryptamine2C receptors in Ca2+-dependent ethanol potentiation of GABA release onto ventral tegmental area dopamine neurons. J Pharmacol Exp Ther. 2009 May;329(2):625-33.
- [1]. Blackburn TP, et al. The acute and chronic administration of the 5-HT(2B/2C) receptor antagonist SB-200646A significantly alters the activity of spontaneously active midbrain dopamine neurons in the rat: An in vivo extracellular single cell study. Synapse. 2006 Jun 15;59(8):502-12.
- [1]. Blackburn TP, et al. The acute and chronic administration of the 5-HT(2B/2C) receptor antagonist SB-200646A significantly alters the activity of spontaneously active midbrain dopamine neurons in the rat: An in vivo extracellular single cell study. Synapse. 2006 Jun 15;59(8):502-12.
- [2]. Kennett GA, et al. In vivo propert
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
