Salmeterol Xinafoate 昔美酸沙美特罗

CAS 94749-08-3 MFCD00897708

化学结构图

94749-08-3
SMILES: OCC1=CC(=CC=C1O)C(O)CNCCCCCCOCCCCC1C=CC=CC=1.OC(=O)C1C=CC2C=CC=CC=2C=1O

化学属性

Mol. FormulaC25H37NO4· C11H8O3
Mol. Weight603.75

别名和识别编码

Chemical NameSalmeterol Xinafoate
CAS Number94749-08-3
Synonym ######## Salmeterol xinafoate
MDL NumberMFCD00897708
PubChem Substance ID24278713
Chemical Name Translation昔美酸沙美特罗
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SNA} Adrenergics, Adrenergics - Agonists, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives, S

产品应用

  • A ?2-Adrenergic agonist. Structural analog of Albuterol (A514500).

相关文献及参考

  • [2]. Malcolm Johnson. Effects of beta2-agonists on resident and infiltrating inflammatory cells. J Allergy Clin Immunol. 2002 Dec;110(6 Suppl):S282-90.
  • [3]. Zhiyuan Wang, et al. Efficacy of salmeterol and formoterol combination treatment in mice with chronic obstructive pulmonary disease. Exp Ther Med. 2018 Feb;15(2):1538-1545.
  • Johnson, M.: Lung, 168, Suppl., 115 (1990),
  • Ullman, A., et al.: Am. Rev. Resp. Dis., 142, 571 (1990),
  • [1]. Panayiotis A Procopiou, et al. The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem. 2011 Oct 15;19(20):6026-32.
  • [1]. Panayiotis A Procopiou, et al. The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem. 2011 Oct 15;19(20):6026-32.
  • [2]. Malcolm Johnson. Effects of beta2-agonists on resident and infiltrating inflammatory cells. J Allergy Clin Immunol. 2002 Dec;110(6 Suppl):S282-90.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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