GR 79236X
CAS 124555-18-6 MFCD00884605
化学结构图
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2C(N[C@H]3CCC[C@@H]3O)=NC=NC1=2
化学属性
| Mol. Formula | C15H21O5N5 |
|---|---|
| Mol. Weight | 351.36 |
别名和识别编码
| Chemical Name | GR 79236X |
|---|---|
| Synonym | GR 79236X N-[(1S, trans)-2-Hydroxycyclopentyl]adenosine |
| MDL Number | MFCD00884605 |
| PubChem Substance ID | 329799944 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Approved Therapeutics/Drug Candidates, Diversification Ready Pharma-Developed Compounds, Fluorination Ready Pharma-Developed Compounds, GPCR Modulators,
- {SNA} Adenosines/P2 Nucleotide Receptor - Agonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Agonists, Approved Therapeutics/Drug Candidates, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives
- {SNA} Adenosines/P2 Nucleotide Receptor - Agonist
相关文献及参考
- [2]. Sneyd JR, et al. Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction. Br J Anaesth. 2007 May;98(5):672-676.
- [3]. P Strong, et al. Suppression of non-esterified fatty acids and triacylglycerol in experimental animals by the adenosine analogue GR79236. Clin Sci (Lond). 1993 Jun;84(6):663-9.
- [1]. L J Knutsen, et al. N-substituted adenosines as novel neuroprotective A(1) agonists with diminished hypotensive effects. J Med Chem. 1999 Sep 9;42(18):3463-77.
- [1]. L J Knutsen, et al. N-substituted adenosines as novel neuroprotective A(1) agonists with diminished hypotensive effects. J Med Chem. 1999 Sep 9;42(18):3463-77.
- [2]. Sneyd JR, et al. Multicentre evaluation of the adenosine agonist GR79236X in patients with dental pain after third molar extraction. Br J Anaesth. 2007 May;98(5):672-676.
- [3]. P Strong, et al. Suppression of non-esterified fatty acids and triacylglycerol i
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
