4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone 5-氟-1-(2R,5S)-[2-羟甲基-1,3-氧硫环-5-酰]胞嘧啶
CAS 143491-57-0 MFCD43491570
化学结构图
SMILES: NC1=N[14C](=O)N(C=C1F)[C@H]1CS[C@@H](CO)O1
化学属性
| Mol. Weight | 247.25 |
|---|---|
| Mol. Formula | C8H10FN3O3S |
别名和识别编码
| CAS Number | 143491-57-0 |
|---|---|
| Chemical Name | 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone |
| Synonym | 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone (-)-2?,3?-Dideoxy-5-fluoro-3?-thiacytidine (-)-2'-Deoxy-5-fluoro-3'-thiacytidine |
| Chemical Name Translation | 5-氟-1-(2R,5S)-[2-羟甲基-1,3-氧硫环-5-酰]胞嘧啶 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Carbohydrates & Derivatives
- Chiral Reagents
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
产品应用
- A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L1725
相关文献及参考
- Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992),
- Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996),
- Feng, J.Y., et al.: FASEB J., 13, 1511 (1999),
