Gemcitabine
CAS 103882-84-4 MFCD00869720
化学结构图
SMILES: NC1C=CN([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)C(=O)N=1 |&1:5,7,10|
化学属性
| Mol. Formula | C9H11F2N3O4 |
|---|---|
| Mol. Weight | 263.23 |
别名和识别编码
| Chemical Name | Cytosine,1-(2-deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)- |
|---|---|
| CAS Number | 103882-84-4 |
| Alfabeta Name | GEMCITABINE |
| MDL Number | MFCD00869720 |
| Synonym | 2(1H)-Pyrimidinone, 2',2'-Difluorodeoxycytidine |
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安全信息
TYPE OF TEST : Micronucleus test TEST SYSTEM : Human Fibroblast DOSE/DURATION : 2 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 393,165,1997
TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 30 nmol/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 51,6110,1991
TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 4 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 393,165,1997
TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 1 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 393,165,1997
TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 3 umol/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 48,4024,1988
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 1 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 393,165,1997
TYPE OF TEST : Micronucleus test TEST SYSTEM : Rodent - hamster Lung DOS
