Balsalazide
CAS 80573-04-2 MFCD00868204
化学结构图
SMILES: OC(=O)CCNC(=O)C1C=CC(=CC=1)/N=N/C1C=C(C(O)=CC=1)C(O)=O
化学属性
| Mol. Formula | C17H15N3O6 |
|---|---|
| Mol. Weight | 357.35 |
别名和识别编码
| Chemical Name | Benzoic acid,5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-, (E)- |
|---|---|
| CAS Number | 80573-04-2 |
| Synonym | 5-[(1E)-2-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxybenzoic Acid Balsalazido Balsalazide (E)-5-((4-(((2-Carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic (E)- |
| Chemical Name Translation |
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分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- An analogue of Sulfasalazine (S699084). A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-?-alanine. Anti-inflammatory (gastrointestinal).
相关文献及参考
- Prakash, A., et al.: Drugs, 56, 83 (1998),
安全信息
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,313,1984
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,313,1984
