Drospirenone 屈螺酮
CAS 67392-87-4 MFCD00867350
化学结构图
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1[C@@H]1C[C@@H]1[C@]12CCC(=O)O1)[C@H]1C[C@H]1C1=CC(=O)CC[C@@]13C
化学属性
| Mol. Formula | C24H30O3 |
|---|---|
| Mol. Weight | 366 |
| Melting Point | 199.0 to 203.0 deg-C |
别名和识别编码
| Chemical Name | Drospirenone |
|---|---|
| Synonym | 6β,7β,15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone 6β,7β,15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone Dihydrospirorenone 6β,7β:15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone 6β,7β:15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone Dihydrospirorenone Dihydrospirorenone |
| MDL Number | MFCD00867350 |
| CAS Number | 67392-87-4 |
| EC Number | 266-679-2 |
| PubChem Substance ID | 172089115 |
| LabNetwork Molecule ID | LN01290259 |
| Chemical Name Translation | 屈螺酮 |
| Reaxys-RN | 4765500 |
| Merck Number | 3454 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Bayer, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, DIG-DY, Hormones, Progesterone, Steroid Hormones
- Approved Therapeutics/Drug Candidates, Bayer, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience
- {SNA} Approved Therapeutics/Drug Candidates, Bayer, Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, DIG-DY, Hormones, Progesterone, Steroid Hormones, 生物活性小分子, 细胞信号转导和神经科学,
相关文献及参考
- Jick SS, Hernandez RK., Risk of non-fatal venous thromboembolism in women using oral contraceptives containing drospirenone compared with women using oral contraceptives containing levonorgestrel: case-control study using United States claims data. Br. Med. J. 343 , d2151, (2011)
- Tang M, Naidu D, Hearing P, Handwerger S, Tabibzadeh S., LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role. Endocrinology 151 , 1320-1330, (2010)
- Africander D, Verhoog N, Hapgood JP, Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception. Steroids 76 , 636-652, (2011)
安全信息
GHS Symbol
- P308+P313
- P201 Obtain special instructions before use. 使用前获取专门指示。
- H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R60 May impair fertility 可能降低生殖能力
