Adefovir 阿德福韦
CAS 106941-25-7 MFCD00866943
化学结构图
SMILES: NC1=NC=NC2=C1N=CN2CCOCP(O)(O)=O
化学属性
| Mol. Formula | C8H12N5O4P |
|---|---|
| Mol. Weight | 273 |
别名和识别编码
| Chemical Name | Adefovir |
|---|---|
| CAS Number | 106941-25-7 |
| Alfabeta Name | AMINOPURINYLETHOXYMETHYLPHOSPHONICACID H2699((()))------- |
| MDL Number | MFCD00866943 |
| Synonym | PMEA 9-(2-phosphonylmethoxyethyl)adenine ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid GS 0393 GS-393 GS 0393 GS-393 P-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid, 9-(2-phosphonylmethoxyethyl)adenine PMEA |
| Chemical Name Translation | 阿德福韦 |
| Beilstein Registry Number | 3561094 |
| LabNetwork Molecule ID | LN00176606 |
| PubChem Substance ID | 329825251 |
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资金保障
专业采购外包团队在线服务
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分类
- {SNA} A-AM, AIDS and Viral Research Reagents, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Immune Cell Signaling and Blood, Immune System Regulation
- Heterocycles
- Pharmaceuticals
- {SNA} A-AM, AIDS and Viral Research Reagents, Bioactive Small Molecule Alphabetical Index, Immune Cell Signaling and Blood, Immune System Regulation, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Intermediates & Fine Chemicals
- Aromatics
产品应用
- Used as an antiviral.
相关文献及参考
- Cundy, K.C., et al.: Antimicrob. Ag. Chemother., 39, 2401 (1995),
- Naesens, L. et al.: Antiviral Chem. Chemother., 8, 1 (1997),
- Kahn, J., et al.: J. Am. Med. Assoc., 282, 2305 (1999),
安全信息
GHS Symbol
- H301 Toxic if swallowed 吞食有毒
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 40,1072,1996
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 40,1072,1996
TYPE OF TEST : Specific locus test ROUTE OF EXPOSURE : Oral TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 100 ppm REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 311,305,1994
