CAS 26864-56-2 MFCD00866714-Penfluridol 五氟利多 TAO{mole}

Penfluridol 五氟利多

CAS 26864-56-2 MFCD00866714

化学结构图

SMILES: OC1(CCN(CCCC(C2C=CC(F)=CC=2)C2C=CC(F)=CC=2)CC1)C1=CC(=C(Cl)C=C1)C(F)(F)F

化学属性

Mol. Formula	C28H27ClF5NO
Mol. Weight	524
Melting Point	106-110
Appearance	五氟利多(26864-56-2)为白色或类白色结晶性粉末；无臭，无味。五氟利多(26864-56-2)在甲醇、乙醇、丙醇或氯仿中易溶；在水中几乎不溶。熔点五氟利多(26864-56-2)的熔点为105～108℃ powder
Solubility	H2O: insoluble

别名和识别编码

Chemical Name	Penfluridol
CAS Number	26864-56-2
Alfabeta Name	BISFLUOROPHENYLBUTYLCHLOROTRIFLUOROMETHYLPHENYLPIPERIDINOL 14444434(((())))----------,
MDL Number	MFCD00866714
Synonym	1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluorom 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol R16341 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol 1-[4,4-Bis(p-flurophenyl)butyl]-4-(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)-4-piperidinol 1-[4,4-双(4-氟苯基)丁基]-4-[4-氯-3-(三氟甲基)苯基]-4-哌啶醇 4-piperidinol,1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethy PENFLURIDOL CP2005 PHENFLURIDOL Penfluridol Penfuridol R16341 R16341, 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol TLP-607 {} {} {} {} {Chemical 五氟利多五氟利多 CP2005
EC Number	248-074-5
Chemical Name Translation	五氟利多
Reaxys-RN	1558826
Merck Number	7087
PubChem Substance ID	253660023
Wiswesser Line Notation	T6NTJ A3YR DF&R DF& DQ DR DG CXFFF
Beilstein Registry Number	1558826

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

Warnings IRRITANT

GHS Symbol

WGK Germany3

Hazard statements

H301 Toxic if swallowed 吞食有毒

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

RTECSTN6957000

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P301+P310
P301+P310+P330
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Hazard Codes 6.1 T

Risk Statements

R25 Toxic if swallowed 吞咽有毒

Hazard Class6.1

UN Number 2811 UN 2811 6.1/PG 3

Storage condition 0-10°C 2-8°C

Packing GroupIII

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   11,139,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 87 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   11,139,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJPHAZ European Journal of Pharmacology.  (Elsevier Science Pub. B.V., POB
   211, 1000 AE Amsterdam, Netherlands)  V.1-    1967- Volume(issue)/page/year:
   11,139,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 171 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
REFERENCE :
   DECRDP Drugs under Experimental and Clinical Research.  (Bioscience
   Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland)  V.1-    1977-
   Volume(issue)/page/year: 4,1,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 20 mg/kg
SEX/DURATION            : female 7-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,581,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 12 mg/kg
SEX/DURATION

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 48 mg/kg
SEX/DURATION            : female 7-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - stillbirth
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,581,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 12 mg/kg
SEX/DURATION            : female 7-12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 13,581,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 48 mg/kg
SEX

其他信息

下游产品:N-乙氧羰基-4-哌啶酮
上游原料:氟化苯
MOL 文件:26864-56-2.mol
MSDS 信息:Penfluridol(26864-56-2).msds
用途二:适用于各型精神病。
color:white
Sigma Aldrich:26864-56-2(sigmaaldrich)
用途一:口服长效抗精神病药