Olanzapine 奥氮平
CAS 132539-06-1 MFCD00866702
化学结构图
SMILES: Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1
化学属性
| Mol. Formula | C17H20N4S |
|---|---|
| Mol. Weight | 312 |
| Melting Point | 192-196 |
别名和识别编码
| Chemical Name | Olanzapine |
|---|---|
| Synonym | 2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine LY-170053 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, LY-170053 |
| MDL Number | MFCD00866702 |
| Beilstein Registry Number | 7655141 |
| Chemical Name Translation | 奥氮平 |
| Reaxys-RN | 7655141 |
| CAS Number | 132539-06-1 |
| Merck Number | 6822 |
| PubChem Substance ID | 160871343 |
| LabNetwork Molecule ID | LN00189132 |
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分类
- {SNA} Agonists, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Diversification Ready Pharma-Developed Compounds, Dopaminargics - Antagonists, Dopaminergics, Eli Lilly, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, O, Serotonergics, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
- {SNA} Agonists, Antagonists, Approved Therapeutics/Drug Candidates, Biochemicals and Reagents, Cell Biol
相关文献及参考
- [2]. Olanzapine for Injection, powder, for solution for intramuscular use.
- [3]. Vucicevic L, et al. Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine. Autophagy. 2014;10(12):2362-78.
- [4]. Karpel-Massler G, et al. Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect. J Neurooncol. 2015 Mar;122(1):21-33.
- [5]. Coccurello R, et al. Chronic administration of olanzapine induces metabolic and food intake alterations: a mousemodel of the atypical antipsychotic-associated adverse effects. Psychopharmacology (Berl). 2006 Jul;186(4):561-71.
- [1]. APPROVED AGREED-UPON LABELING.
- [1]. APPROVED AGREED-UPON LABELING.
- [2]. Olanzapine for Injection, powder, for solution for intramuscular use.
- [3]. Vucicevic L, et al. Autophagy inhibition uncovers the neurotoxic action of the antipsychoti
安全信息
GHS Symbol
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310+P330
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- P332+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H301 Toxic if swallowed 吞食有毒
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
