PICLAMILAST
CAS 144035-83-6 MFCD00864786
化学结构图
SMILES: COC1C=CC(=CC=1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl
化学属性
| Mol. Formula | C18H18Cl2N2O3 |
|---|---|
| Mol. Weight | 381.257 |
别名和识别编码
| Chemical Name | PICLAMILAST |
|---|
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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相关文献及参考
- [2]. Manuel Mata, et al. Piclamilast inhibits the pro-apoptotic and anti-proliferative responses of A549 cells exposed to H(2)O(2) via mechanisms involving AP-1 activation. Free Radic Res. 2012 May;46(5):690-9.
- [3]. Edoardo Parrella, et al. Phosphodiesterase IV inhibition by piclamilast potentiates the cytodifferentiating action of retinoids in myeloid leukemia cells. Cross-talk between the cAMP and the retinoic acid signaling pathways. J Biol Chem . 2004 Oct 1;279(40):42026-40.
- [4]. T Ukita, et al. Novel, potent, and selective phosphodiesterase-4 inhibitors as antiasthmatic agents: synthesis and biological activities of a series of 1-pyridylnaphthalene derivatives. J Med Chem. 1999 Mar 25;42(6):1088-99.
- [1]. M J
- [1]. M J Ashton, et al. Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues. J Med Chem. 1994 May 27;37(11):1696-703.
