Candesartan 坎地沙坦
CAS 139481-59-7 MFCD00864463
化学结构图
SMILES: CCOC1=NC2C=CC=C(C=2N1CC1C=CC(=CC=1)C1=CC=CC=C1C1NN=NN=1)C(O)=O
化学属性
| Mol. Formula | C24H20N6O3 |
|---|---|
| Mol. Weight | 440 |
| Melting Point | 155-161 |
别名和识别编码
| Chemical Name | Candesartan |
|---|---|
| CAS Number | 139481-59-7 |
| Alfabeta Name | TETRAZOLYLBIPHENYLYLMETHYLETHOXYBENZOIMIDAZOLECARBOXYLICACID HHD1215114217[[]]((()))---------------,'' |
| MDL Number | N/A |
| Synonym | 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid |
| Chemical Name Translation | 坎地沙坦 |
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Aromatics
- Heterocycles
- Nucleotides
- Bases & Related Reagents
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- An angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.
相关文献及参考
- [2]. Nishimura Y, et al. Chronic peripheral administration of the angiotensin II AT(1) receptor antagonist candesartan blocks brain AT(1) receptors. Brain Res. 2000 Jul 14;871(1):29-38.
- Kaur, N., et al.: Bioorg. Med. Chem., 16, 10210 (2008),
- [1]. Pfeffer MA, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003 Sep 6;362(9386):759-66.
- [1]. Pfeffer MA, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003 Sep 6;362(9386):759-66.
- [2]. Nishimura Y, et al. Chronic peripheral administration of the angiotensin II AT(1) receptor antagonist candesartan blocks brain AT(1) receptors. Brain Res. 2000 Jul 14;871(1):29-38.
安全信息
GHS Symbol
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
