Doxycycline hyclate 盐酸强力霉素
CAS 24390-14-5 MFCD00800994
化学结构图
SMILES: O.Cl.Cl.CCO.CN(C)[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](C)C4C=CC=C(O)C=4C(=O)C3=C(O)[C@@]2(O)C(=O)C(=C1O)C(N)=O.CN(C)[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](C)C4C=CC=C(O)C=4C(=O)C3=C(O)[C@@]2(O)C(=O)C(=C1O)C(N)=O |&1:9,10,11,13,14,28,41,42,43,45,46,60|
化学属性
| Mol. Formula | C22H24N2O8.1/2C2H6O.HCl.1/_ |
|---|---|
| Mol. Weight | 444.44 |
别名和识别编码
| Chemical Name | Doxycycline hyclate |
|---|---|
| EC Number | 209-271-1 |
| Synonym | (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
| CAS Number | 24390-14-5 |
| Chemical Name Translation | 盐酸强力霉素 |
| MDL Number |
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相关文献及参考
- [2]. Luger AL, et al. Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems. Int J Mol Sci. 2018 May 17;19(5).
- [3]. Eusebio Manchado, et al. A combinatorial strategy for treating KRAS-mutant lung cancer. Nature. 2016 Jun 30;534(7609):647-51.
- [1]. Wilfried Briest, et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7.
- [1]. Wilfried Briest, et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7.
- [2]. Luger AL, et al. Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems. Int J Mol Sci. 2018 May 17;19(5).
