2-Chloro-5-(trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride) 2-氯-5-三氟甲基苯硼酸

CAS 182344-18-9 MFCD00797335

化学结构图

182344-18-9
SMILES: OB(O)C1=CC(=CC=C1Cl)C(F)(F)F

化学属性

Mol. FormulaC7H5BClF3O2
Mol. Weight224
TSCANo
Density1.49

别名和识别编码

Chemical Name2-Chloro-5-(trifluoromethyl)phenylboronic Acid (contains varying amounts of Anhydride)
CAS Number182344-18-9
Alfabeta NameCHLOROTRIFLUOROMETHYLPHENYLBORONICACID 25()---
MDL NumberMFCD00797335
Synonym 2-氯-5-(三氟甲基)苯硼酸 2-Chloro-5-(trifluoromethyl)phenylboronic acid 2-Chloro-5-(trifluoromethyl)benzeneboronic acid
Reaxys-RN11060805
EC Number250-023-7
Beilstein Registry Number2384789
Chemical Name Translation2-氯-5-三氟甲基苯硼酸
PubChem Substance ID135727335
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分类

  • Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents
  • {SA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents
  • {SNA} Aryl Boronic Acids,

相关文献及参考

  • 1. Lipeeva, A. V.; et al., Plant coumarins: VIII. Suzuki reaction in the synthesis of 3-aryl(hetaryl)furocoumarins Russ. J. Org. Chem. 47 , 1404-1409, (2011)
  • 2. Ioannidou, H. A.; et al., Three-Step Synthesis of Ethyl Canthinone-3-carboxylates from Ethyl 4-Bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-Catalyzed Suzuki-Miyaura Coupling and a Cu-Catalyzed Amidation Reaction J. Org. Chem. 76 , 5113-5122, (2011)
  • 3. LaBeaume, P.; et al., An efficient route to xanthine based A2A adenosine receptor antagonists and functional derivatives Org. Biomolecular Chem. 8 , 4155-4157, (2010)
  • 4. Gollner, A.; Koutentis, P. A., Two-Step Total Syntheses of Canthin-6-one Alkaloids: New One-Pot Sequential Pd-Catalyzed Suzuki-Miyaura Coupling and Cu-Catalyzed Amidation Reaction Org. Lett. 12 , 1352-1355, (2010)

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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