CAS 93106-60-6 MFCD00792463-Enrofloxacin 恩氟沙星 TAO{mole}

Enrofloxacin 恩氟沙星

CAS 93106-60-6 MFCD00792463

化学结构图

SMILES: CCN1CCN(CC1)C1=CC2=C(C=C1F)C(=O)C(=CN2C1CC1)C(O)=O

化学属性

Mol. Formula	C19H22FN3O3
Mol. Weight	359.40
TSCA	No
Melting Point	222-228

别名和识别编码

Chemical Name	Enrofloxacin
CAS Number	93106-60-6
Synonym	1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-quinolinecarboxylic acid BAY VP 2674 Baytril 恩氟沙星 Enrofloxacin 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo 恩诺沙星
MDL Number	MFCD00792463
PubChem Substance ID	87560805
Beilstein Registry Number	5307824
Merck Number	3592
Reaxys-RN	5307824
Chemical Name Translation	恩氟沙星

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分类

{SNA} A - K, Antibacterial, Antibiotics A to Z, Antibiotics A-F, Chemical Structure Class, Inhibits an Enzyme, Interferes with DNA Synthesis, Mechanism of Action, Quinolones and Fluoroquinolones, Spectrum of Activity, 抗生素, 生化试剂
{SNA} 1694 Pharmaceuticals & Personal Care Products, A - K, APIs & Metabolites, APIs (Active Pharmaceutical Ingredients) & Metabolites, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Biochemicals and Reagents,

产品应用

Fluorinated quinolone antibacterial.

安全信息

WGK Germany3

RTECSVB1993650

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Signal word

Hazard statements

H303 May be harmfully swallowed 吞食可能有害

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

GHS Symbol

Safety Statements

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4336 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und
   Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1-
   1976-  Volume(issue)/page/year: 2,87,1987

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 60 ng/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 248,135,1991