8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphate sodium salt
CAS 51239-26-0 MFCD00674888
化学结构图
SMILES: [Na+].NC1NC(=O)C2N=C(SC3C=CC(Cl)=CC=3)N([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C=2N=1
化学属性
| Mol. Formula | C16H14ClN5NaO7PS |
|---|---|
| Mol. Weight | 509.79 |
别名和识别编码
| Chemical Name | 8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphate sodium salt |
|---|---|
| Synonym | 8-(4-Chlorophenylthio)-guanosine 3',5'-cyclic monophosphate sodium salt 8-pCPT-cGMP 8-pCPT-cGMP pCPT-cGMP pCPT-cGMP |
| MDL Number | MFCD00674888 |
| PubChem Substance ID | 24892786 |
| CAS Number | 51239-26-0 |
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分类
- Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, G Proteins and Cyclic Nucleotides, Kinase/Phosphatase Biology, Protein Kinase G (PKG), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology
- {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Cyclic Nucleotide Metabolism, Cyclic Nucleotides and Analogs, G Proteins and Cyclic Nucleotides, Kinase/Phosphatase Biology, Protein Kinase G (PKG), Serine/Threonine Kinase Activators, Serine/Threonine Kinase Biology, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Sm
相关文献及参考
- VanUffelen, B.E., et al., Interaction of cyclic GMP and cyclic AMP during neutrophil migration: involvement of phosphodiesterase type III. Biochem. Pharmacol. 56 , 1061-1063, (1998) 摘要
- Wei, J.Y., et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J. Mol. Neurosci. 10 , 53-64, (1998) 摘要
- He, P., et al., cGMP modulates basal and activated microvessel permeability independently of [Ca 2+ ]i. Am. J. Physiol. 274(6 Pt 2) , H1865-H1874, (1998)
- Hood, J., and Granger, H.J., Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells. J. Biol. Chem. 273 , 23504-23508, (1998) 摘要
- Suhasini, M., et al., Cyclic-GMP-dependent protein kinase inhibits the ras/mitogen-activated protein kinase pathway. Mol. Cell. Biol. 18 , 6983-6994, (1998) 摘要
