CTAP
CAS 103429-32-9 MFCD00671434
化学结构图
SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC2=CNC3C=CC=CC=32)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CSSC(C)(C)[C@H](NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H](N)CC1C=CC=CC=1
化学属性
| Mol. Formula | C51H69N13O11S2 |
|---|---|
| Mol. Weight | 1104.30 |
别名和识别编码
| Chemical Name | CTAP |
|---|---|
| MDL Number | MFCD00671434 |
| CAS Number | 103429-32-9 |
| Synonym | CTAP |
| PubChem Substance ID | 329775120 |
| Chemical Name Translation |
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分类
- {SNA} Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology
- Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology
- {SNA} Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- Abbruscato, T.J., et al., Blood-brain barrier permeability and bioavailability of a highly potent and mu-selective opioid receptor antagonist CTAP: comparison with morphine. J. Pharmacol. Exp. Ther. 280 , 402, (1997) 摘要
- Bilsky, E., et al., Effects of naloxone and D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH 2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice. J. Pharmacol. Exp. Ther. 277 , 484, (1996) 摘要
- Yang, Y.R., et al., Structure-activity relationships of naturally occurring and synthetic opioid tetrapeptides acting on locus coeruleus neurons. Eur. J. Pharmacol. 372 , 229-236, (1999) 摘要
- [1]. Mitchell J Bartlett, et al. Highly-selective µ-opioid Receptor Antagonism Does Not Block L-DOPA-induced Dyskinesia in a Rodent Model.BMC Res Notes
安全信息
其他信息
- Amino Acid Sequence Phe-Cys-Tyr-Trp-Arg-Thr-Pen-Thr-NH2
