2-(4-(4-(2-Methoxyphenyl)Piperazin-1-Yl)Butyl)Isoindoline-1,3-Dione Hydrobromide 2-(4-(4-(2-甲氧基苯基)哌嗪-1-基)丁基)异吲哚啉-1,3-二酮氢溴酸盐
CAS 115338-32-4 MFCD00078590
化学结构图
SMILES: Br.COC1=CC=CC=C1N1CCN(CCCCN2C(=O)C3=CC=CC=C3C2=O)CC1
化学属性
| Mol. Formula | C23H27N3O3· HBr |
|---|---|
| Mol. Weight | 474.39 |
别名和识别编码
| Chemical Name | 2-(4-(4-(2-Methoxyphenyl)Piperazin-1-Yl)Butyl)Isoindoline-1,3-Dione Hydrobromide |
|---|---|
| Synonym | 1-(2-Methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide NAN-190 hydrobromide |
| MDL Number | MFCD00078590 |
| PubChem Substance ID | 24278108 |
| Chemical Name Translation | 2-(4-(4-(2-甲氧基苯基)哌嗪-1-基)丁基)异吲哚啉-1,3-二酮氢溴酸盐 |
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分类
- {SNA} Antagonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, N, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives, Serotonergics, Serotonergics - Antagonists
- {SNA} Antagonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Serotonergics, Serotonergics - Antagonists, 生化试剂
相关文献及参考
- [2]. Sharifi H, et al. Dose-Dependent Effect of Flouxetine on 6-OHDA-Induced Catalepsy in Male Rats: A Possible Involvement of 5-HT1A Receptors. Adv Pharm Bull. 2013;3(1):203-6.
- [3]. Citó MC, et al. Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system. Braz J Med Biol Res. 2015 Jan;48(1):57-64.
- [1]. Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014 Jan;19(1):66-76.
- [1]. Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014 Jan;19(1):66-76.
- [2]. Sharifi H, et al. Dose-Dependent Effect of Flouxetine on 6-OHDA-Induced Catalepsy in Male Rats: A Possible Involvement of 5-HT1A Receptors. Adv Pharm Bull. 2013;3(1):203-6.
- [3]. Citó MC, et al. Antidepressant-like effect of Hoodia go
安全信息
GHS Symbol
- P273 Avoid release to the environment. 避免释放到环境中。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R50 Very toxic to aquatic organisms 对水生生物极毒
