Dicarbine (Dihydrochloride) 2,8-二甲基-2,3,4,4a,5,9b-六氢-1H-吡啶并[4,3-b]吲哚二盐酸盐

CAS 33162-17-3 MFCD00444963

化学结构图

33162-17-3
SMILES: Cl.Cl.CC1C=CC2NC3CCN(C)CC3C=2C=1

化学属性

Mol. FormulaC13H20Cl2N2
Mol. Weight275.22

别名和识别编码

Chemical NameDicarbine (Dihydrochloride)
CAS Number33162-17-3
Alfabeta NameDIMETHYLHEXAHYDROPYRIDOINDOLEDIHYDROCHLORIDE ABHB28234459143[]-------,,,,,,,
MDL NumberMFCD00444963
Synonym Carbidine dihydrochloride 2,8-Dimethyl-1,2,3,4,4a,9b-hexahydro-gamma-carboline dihydrochloride 1,2,3,4,4a,9b-Hexahydro-2,8-dimethyl-5H-pyrido(4,3-b)indole Carbidin Carbidine 2,8-Dimethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole dihydrochloride
Chemical Name Translation2,8-二甲基-2,3,4,4a,5,9b-六氢-1H-吡啶并[4,3-b]吲哚二盐酸盐
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分类

  • {SNA} Building Blocks, C12 to C15, C13 to C15, C13 to C27, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Indoles, Pyridines

相关文献及参考

安全信息

Warnings IRRITANT
RTECSUU9990250
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 87 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - antipsychotic
   Behavioral - analgesia
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 6,512,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EKFAE9 Eksperimental'naya i Klinicheskaya Farmakologiya.  Experimental and
   Clinical Pharmacology. (Mezhdunarodnaya Kniga, ul. B. Yakimanka, 39, 117049
   Moscow, Russia)  V.55-    1992-  Volume(issue)/page/year: 57(2),4,1994

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 35,102,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 87 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd.

系列性分类


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