Benfotiamine 苯磷硫胺
CAS 22457-89-2 MFCD00057343
化学结构图
SMILES: C/C(=C(/CCOP(O)(O)=O)\SC(=O)C1C=CC=CC=1)/N(CC1=CN=C(C)N=C1N)C=O
化学属性
| Mol. Formula | C19H23N4O6PS |
|---|---|
| Mol. Weight | 466 |
别名和识别编码
| Chemical Name | Benfotiamine |
|---|---|
| Synonym | Benfotiamine |
| MDL Number | MFCD00057343 |
| PubChem Substance ID | 253662524 |
| CAS Number | 22457-89-2 |
| EC Number | 245-013-4 |
| Reaxys-RN | 771326 |
| Chemical Name Translation | 苯磷硫胺 |
| Merck Number | 1041 |
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分类
- Nutrition Research, Vitamin B, Vitamin B1, Vitamins
- {SNA} Vitamin B, Vitamin B1, Vitamins, 细胞生物学, 营养研究
- {SNA} Nutrition Research, Vitamin B, Vitamin B1, Vitamins
- {SNA} Vitamin B, Vitamin B1, Vitamins, 生化试剂
相关文献及参考
- WADA T, TAKAGI H, MINAKAMI H, et al., A new thiamine derivative, S-benzoylthiamine O-monophosphate. Science 134 , 195-196, (1961) 摘要
- Ziems M, Netzel M, Bitsch I., Biokinetic parameters and metabolism of S-benzoylthiamine-O-monophosphate. Biofactors 11 , 109-110, (2000) 摘要
- Volvert ML, Seyen S, Piette M, et al., Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives. BMC Pharmacol. 8 , 10, (2008) 摘要
- Balakumar P, Rohilla A, et al., The multifaceted therapeutic potential of benfotiamine. Pharmacol. Res. 61 , 482-488, (2010) 摘要
- Yadav UC, Kalariya NM, et al., Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages. Free Radic. Biol. Med. 48 , 1423-1434, (2010) 摘要
- Du Y, Kowluru A, Kern TS., PP2A contributes to endothelial death in high glucose: inhibition by benfotiamine. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299 , R1610-R1617, (2010) 摘要
- Kihm LP, Müller-Krebs S, Klein J, et al., Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis. J. Am. Soc. Nephrol. 22 , 914-926, (2011) 摘要
- Merck 14 ,1041
