CAS 33795-24-3 MFCD00274163
化学结构图
SMILES: Cl.CNC1(CCCCC1=O)C1C=CC=CC=1Cl
化学属性
| Mol. Formula | C13H16ClNO · HCl |
|---|---|
| Mol. Weight | 274.19 |
别名和识别编码
| Chemical Name | |
|---|---|
| CAS Number | 33795-24-3 |
| Synonym | (2R)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride (+)- 2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone Hydrochloride (-)-(R)-Ketamine Hydrochloride (R)-(+)-Ketamine Hydrochloride S-(+)-Ketamine hydrochloride |
| MDL Number | MFCD00274163 |
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分类
- Amines
- Aromatics
- Neurochemcals
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Ion Channels, Ionotropic Glutamate Receptor Modulators, K, Ligand-Gated Ion Channels, NMDA Antagonists, Neuroscience, Neurotransmission, Neurotransmitters, Pfizer Compounds
产品应用
- (R)-Ketamine is the less active enantiomer of the NMDA receptor antagonist and anesthetic agent Ketamine (K165300).
相关文献及参考
- Meliska, C.J. et al.: J. Pharmacol Exp. Therap., 212, 206 (1980); Smith, D.J. et al.: Neuropharmacology, 20, 391 (1981); Klockgether-Radke, A.P. et al.: Eur. J. Anaesthesiol., 22, 215 (2005);
安全信息
GHS Symbol
- P305+P351+P338
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- H315 Causes skin irritation 会刺激皮肤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H351 Suspected of causing cancer 怀疑致癌
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R22 Harmful if swallowed 吞咽有害
