Methylprednisolone hemisuccinate 琥珀酸甲泼尼龙

CAS 2921-57-5 MFCD00271782

化学结构图

2921-57-5
SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)COC(=O)CCC(=O)O)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12

化学属性

Mol. FormulaC26 H34 O8
Mol. Weight474.54
Melting Point>230°C (dec.)
Boiling Point
Flash Point-

别名和识别编码

Chemical Name6α-Methylprednisolone 21-Hemisuccinate
MDL Number-
Chemical Name Translation琥珀酸甲泼尼龙
Synonym (6-alpha,11-beta)-yl 1,4-PREGNADIEN-6-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-HEMISUCCINATE 11beta,17,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-(hydrogen succinate) 11β,17α-Dihydroxy-3,20-dioxo-6α-methylpregna-1,4-diene-21-ol 21-(4-hydroxy-4-oxobutyrate) 21-(3-Carboxy-1-oxopropoxy)-11β,17-dihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione 4-diene-3,20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-21-(hy 4-diene-3,20-dione,11-beta,17,21-trihydroxy-6-alpha-methyl-pregna-21-suc 6 ALPHA-METHYLPREDNISOLONE HEMISUCCINATE 6 alpha-Methylprednisolone Sodium Hemisuccinate 6-methylprednisolonehemisuccinate 6A-METHYLPREDNISOLONEHEMISUCCINATE 6Alpha-Methylprednisolone 21-Hemisuccinate 6a-Methylprednisolone 21-Hemisuccinate {} {} {} {} {} {} {} {}
CAS Number2921-57-5
EC Number220-863-9
LabNetwork Molecule IDLN00191008
PubChem Substance ID16923
InChIInChI=1S/C26H34O8/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31)/t14-,16-,17-,19-,23+,24-,25-,26-/m0/s1
Canonical SMILES-
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相关文献及参考

  • [2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000.
  • [1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6.
  • [1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6.
  • [2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000.

安全信息

Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312
  • P301+P317
  • P302+P352
  • P308+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医,如果你觉得不舒服
  • P317
  • P318
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition +4°C 4 4℃

其他信息

  • MOL 文件:2921-57-5.mol

系列性分类


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