CAS 6164-47-2 MFCD00236406-Protopine, hydrochloride TAO{mole}

Mol. Formula	C20H19NO5·HCl
Mol. Weight	389.83

Chemical Name	Protopine hydrochloride
MDL Number	MFCD00236406
EC Number	228-196-5
Synonym	Protopine hydrochloride
Wiswesser Line Notation	T I5 G6 B-10-65 DN JO LO PV VO A&O KH WH&&T&&J D1 &GH
CAS Number	6164-47-2
PubChem Substance ID	22543
LabNetwork Molecule ID	LN04685175
InChI	InChI=1S/C20H19NO5.ClH/c1-21-5-4-13-7-18-19(25-10-24-18)8-14(13)16(22)6-12-2-3-17-20(15(12)9-21)26-11-23-17;/h2-3,7-8H,4-6,9-11H2,1H3;1H

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分类

{SNA} Alkaloid, Bioactive Small Molecule Alphabetical Index, Calcium Channel Modulators, Inhibitors and Activators, Ion Channels, PI-PZ, Phytochemicals by Chemical Classification, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 营养研究
{SNA} Alkaloid, Bioactive Small Molecules, Calcium Channel Modulators, Cell Biology, Cell Signaling and Neuroscience, Inhibitors and Activators, Ion Channels, Nutrition Research, P, Phytochemicals by Chemical Classification, Voltage-gated Ion Channels

安全信息

GHS Symbol

WGK Germany3

Precautionary statements

P301+P310

Hazard statements

H301 Toxic if swallowed 吞食有毒

RTECSUL2000000

Signal word Danger

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Hazard Codes T

Risk Statements

R25 Toxic if swallowed 吞咽有毒

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 102 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 104,253,1952

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 5,163,1946

Protopine, hydrochloride

CAS 6164-47-2 MFCD00236406

化学结构图

化学属性

别名和识别编码

分类

安全信息

系列性分类

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