(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine

CAS 117857-93-9 MFCD00216830

化学结构图

117857-93-9
SMILES: N[C@@H]([C@H]1C[C@@H]1C(O)=O)C(O)=O

化学属性

Mol. FormulaC6H9NO4
Mol. Weight159.14

别名和识别编码

Chemical Name(2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine
Synonym (2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine L-CCG-1
MDL NumberMFCD00216830
PubChem Substance ID24278353
CAS Number117857-93-9
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分类

  • Bioactive Small Molecules, Biochemicals and Reagents, C-CH, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Agonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Metabotropic Agonists, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives
  • {SA} Bioactive Small Molecules, Biochemicals and Reagents, C-CH, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Agonists, GPCR Modulators,
  • {SNA} Bioactive Small Molecules,

相关文献及参考

  • Yamashita, H., et al., Inhibition by folded isomers of L-2-(carboxycyclopropyl)glycine of glutamate uptake via the human glutamate transporter hGluT-1. Eur. J. Pharmacol. 289 , 387-390, (1995) 摘要
  • Cozzi, et al., Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: In vivo studies with (2S1′S2′S3′R)-2-(2′-carboxy-3′-phenylcyclopropyl)glycine a new potent and selective antagonist. Eur. J. Neurosci. 9 , 1350, (1997)
  • King, et al., Dual action of metabotropic glutamate receptor agonists on neuronal excitability and synaptic transmission in spinal ventral horn neurons in vitro . Neuropharmacology 12 , 1673-1680, (1996) 摘要
  • Toms, et al., The effects of (RS)-α-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG) a potent and selective metabotropic glutamate receptor antagonist. Br. J. Pharmacol. 119 , 851-854, (1996)

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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