Aristolochicacidsodiumsalt 马兜铃酸钠盐
CAS 10190-99-5 MFCD00210760
化学结构图
SMILES: [Na+].COC1=CC=CC2C3=C(C(=CC4OCOC=43)C([O-])=O)C(=CC=21)[N+]([O-])=O
化学属性
| Mol. Formula | C17H10NNaO7 |
|---|---|
| Mol. Weight | 363.25 |
别名和识别编码
| Chemical Name | Aristolochicacidsodiumsalt |
|---|---|
| Synonym | Aristolochic acid sodium salt |
| CAS Number | 10190-99-5 |
| PubChem Substance ID | 24891454 |
| EC Number | 233-463-4 |
| MDL Number | MFCD00210760 |
| Chemical Name Translation | 马兜铃酸钠盐 |
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分类
- AN-AZ, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism
- {SNA} Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism, 细胞信号转导和神经科学, 细胞生物学
- {SNA} AN-AZ, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling, Phospholipase Inhibitors, Phospholipid Metabolism
相关文献及参考
- 1. Levova, K., et al., Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model Toxicol. Sci. 121 , 43-56, (2011)
- Kim, S.H., et al., Drosophila TRPA1 Channel Mediates Chemical Avoidance In Gustatory Receptor Neurons. Proc. Natl. Acad. Sci. U. S. A. 107 , 8440-5, (2010) 摘要
安全信息
GHS Symbol
- H351 Suspected of causing cancer 怀疑致癌
- H331 Toxic if inhaled 吸入中毒
- H311 Toxic in contact with skin 皮肤接触中毒
- H301 Toxic if swallowed 吞食有毒
- P301+P310
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S22 Do not breathe dust 不要吸入粉尘；
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
