(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-Dihydroxy-17-((S)-2-Hydroxy-6-Methylhept-5-En-2-Yl)-4,4,8,10,14-Pentamethylhexadecahydro-1H-Cyclopenta[A]Phenanthren-6-Yl)Oxy)-4,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-Yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-二羟基-17-((S)-2-羟基-6-甲基庚-5-烯-2-基)-4,4,8,10,14-五甲基十六氢-1H-环戊[a]菲-6-基)氧基)-4,5-二羟基-6-(羟甲基)四氢-2H-吡喃-3-基)氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇
CAS 52286-58-5 MFCD00210509
化学结构图
SMILES: CC1(C)[C@@H]2[C@H](C[C@]3(C)[C@H](C[C@@H](O)[C@@H]4[C@H](CC[C@@]34C)[C@@](C)(O)CCC=C(C)C)[C@@]2(C)CC[C@@H]1O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
化学属性
| Mol. Formula | C42H72O14 |
|---|---|
| Mol. Weight | 801 |
| Density | 1.33 |
别名和识别编码
| Chemical Name | (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-Dihydroxy-17-((S)-2-Hydroxy-6-Methylhept-5-En-2-Yl)-4,4,8,10,14-Pentamethylhexadecahydro-1H-Cyclopenta[A]Phenanthren-6-Yl)Oxy)-4,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3-Yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol |
|---|---|
| Synonym | (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside 人参皂甙Rf 人参皂苷 Rf |
| MDL Number | MFCD00210509 |
| CAS Number | 52286-58-5 |
| EC Number | 250-023-7 |
| Beilstein Registry Number | 2384789 |
| Chemical Name Translation | (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-二羟基-17-((S)-2-羟基-6-甲基庚-5-烯-2-基)-4,4,8,10,14-五甲基十六氢-1H-环戊[a]菲-6-基)氧基)-4,5-二羟基-6-(羟甲基)四氢-2H-吡喃-3-基)氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
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分类
- {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, G, Nutrition Research, Panax ginseng, Phytochemicals by Plant (Food/Spice/Herb)
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, G, Nutrition Research, Panax ginseng, Phytochemicals by Plant (Food/Spice/Herb)
- {SNA} Analytical Standards, Isoprenoids, Panax ginseng, Phytochemical Standards, Phytochemicals by Plant (Food/Spice/Herb), 分析/色谱, 细胞生物学, 营养研究
产品应用
- A glycoside found to mediate lipoprotein metabolism
相关文献及参考
- [2]. Mogil JS, et al. Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice. Brain Res. 1998 May 11;792(2):218-28.
- [1]. Nah SY, et al. A trace component of ginseng that inhibits Ca 2+ channels through a pertussis toxin-sensitive G protein. Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8739-43.
- [1]. Nah SY, et al. A trace component of ginseng that inhibits Ca 2+ channels through a pertussis toxin-sensitive G protein. Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8739-43.
- [2]. Mogil JS, et al. Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice. Brain Res. 1998 May 11;792(2):218-28.
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1340 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,539,1975
其他信息
- Ginsenoside Rf, a glycoside of protopanaxatriol from Panax ginseng, is shown to be a biologically active saponin found to regulate lipoprotein metabolism. Mechanistic studies report that this regulation is done via altering of peroxisome proliferator-activated receptor α (PPARα)-mediated pathways. PPARα has demonstrated the ability to regulate C-III mRNA and basal levels of hepatic apoA-I (apolipoprotein A-I) which affect lipoprotein metabolism. Additional experiments have also observed this Ginsenoside Rf's ability to inhibit Ca2+ channels in mammalian sensory neurons in vitro.
