9-(Tetrahydrofuran-2-Yl)-9H-Purin-6-Amine 9-(四氢呋喃-2-基)-9H-嘌呤-6-胺

CAS 17318-31-9 MFCD00210216

化学结构图

17318-31-9
SMILES: Nc1ncnc2c1ncn2C1CCCO1

化学属性

Mol. FormulaC9H11N5O
Mol. Weight205
Melting Point162.0 to 167.0 deg-C

别名和识别编码

Chemical Name9-(Tetrahydrofuran-2-Yl)-9H-Purin-6-Amine
Synonym 9-(Tetrahydro-2-furanyl)-9H-purin-6-amine 9-THF-Ade 9-(tetrahydro-2-furyl)-adenine SQ 22,536 SQ 22536 SQ-22,536 SQ-22536 Sq 22,536
MDL NumberMFCD00210216
PubChem Substance ID5270
Chemical Name Translation9-(四氢呋喃-2-基)-9H-嘌呤-6-胺
Reaxys-RN534250
LabNetwork Molecule IDLN00331351
InChIKeyUKHMZCMKHPHFOT-ZCFIWIBFSA-N
InChIInChI=1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12)
CAS Number17318-31-9
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分类

  • {SNA} Adenylyl Cyclase Inhibitors, Bioactive Small Molecule Alphabetical Index, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, S, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Adenylyl Cyclase Inhibitors, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, S

相关文献及参考

  • [1]. Emery AC, et al. A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536. Mol Pharmacol. 2013 Jan;83(1):95-105.

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition 0-10°C

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. S - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. G Proteins and Cyclic Nucleotides - Cell Signaling and Neuroscience
  5. Cyclic Nucleotide Metabolism - G Proteins and Cyclic Nucleotides
  6. Adenylyl Cyclase Inhibitors - Cyclic Nucleotide Metabolism
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Adenylate Cyclase  (腺苷酸环化酶)

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