2-Chloro-6-Methoxypyridine-4-Carboxylic Acid 2-氯-6-甲氧基吡啶-4-羧酸

CAS 15855-06-8 MFCD00173928

化学结构图

15855-06-8
SMILES: COC1C=C(C=C(Cl)N=1)C(O)=O

化学属性

Mol. FormulaC7H6ClNO3
Mol. Weight188
Melting Point192-200 °C
TSCANo
Boiling Point209-213°
Density

别名和识别编码

Chemical Name2-Chloro-6-Methoxypyridine-4-Carboxylic Acid
CAS Number15855-06-8
Alfabeta NameCHLOROMETHOXYISONICOTINICACID 26---
MDL NumberMFCD00173928
Synonym 2-Chloro-6-methoxyisonicotinic acid 2-氯-6-甲氧基吡啶-4-羧酸 2-氯-6-甲氧基异烟酸
Chemical Name Translation2-氯-6-甲氧基吡啶-4-羧酸
EC Number
Beilstein Registry Number
PubChem Substance ID329762217
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Building Blocks, C7 to C18, C7 to C8, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Pyridines
  • {KO} CarboxylicAcids
  • {SNA} Building Blocks, C7, C7 to C8, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Pyridines

相关文献及参考

  • Adamczyk, M.; et al., Nonproteinogenic amino acids: an efficient asymmetric synthesis of (S)-(-)-acromelobic acid and (S)-(-)-acromelobinic acid Tetrahedron 58 , 6951-6963, (2002)
  • Chellappan, S. K.; et al., Synthesis and Pharmacological Evaluation of Novel 9- and 10-Substituted Cytisine Derivatives. Nicotinic Ligands of Enhanced Subtype Selectivity J. Med. Chem. 49 , 2673-2676, (2006)

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305 IF IN EYES: 如果进入眼睛
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S37 Wear suitable gloves 戴适当手套；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi
UN Number
RTECS
Packing Group

药物吸收、分布、代谢与排泄(ADME)

Lipinski's Rule of 5
Y
H-bond Acceptors
4
Rotatable Bonds
2
H-bond Donors
1
LogP
1

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Pyridines - Halogenated Heterocycles
  6. C7 to C18 - Pyridines
  1. C7 to C8 - Pyridines

相关产品推荐