CAS 9005-66-7 MFCD00165345-Tween 40 吐温40 TAO{mole}

Tween 40 吐温40

CAS 9005-66-7 MFCD00165345

化学结构图

SMILES: CCCCCCCCCCCC(=O)OCCOCC(OCCO)C1OCC(OCCO)C1OCCO

化学属性

Mol. Formula	N/A
Density	1.05
Refractive index	1.4700
TSCA	Yes
Melting Point	0.1 °C
Solubility	100 G/L
Flash Point	268°C(lit.)
Appearance	viscous liquid
Mol. Weight	N/A
Stability	对湿度敏感
Boiling Point	797.89 °C at 760 mmHg

别名和识别编码

MDL Number	MFCD00165345
CAS Number	9005-66-7
Synonym	Polysorbate 40 {LY} Polysorbate 40 {} {LY} Polysorbate 40 {} {} {LY} Polysorbate 40 {} {} {} {LY} Polysorbate 40 {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Polysorbate 40 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY}
EC Number	500-020-4
Chemical Name	Tween 40
PubChem Substance ID	92329579
Chemical Name Translation	吐温40
InChIKey	HMFKFHLTUCJZJO-OQUNMALSSA-N
InChI	InChI=1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3/t22-,23-,25-,26-/m1/s1
Canonical SMILES	[Polysorbate 40]

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分类

{SNA} non-ionic
{SNA} Cell Culture, Detergents, Detergents A to M, Detergents by Applications, Diagnostic Applications, Drug Delivery-Liposomes, Electrophoresis Chromatography, Enzymology, Materials Science, Membrane Protein Solubilization, Micro/NanoElectronics, Non-Ionic Detergents, Nonionic Surfactants, Self Assembly & Contact Printing, Self-Assembly Materials, Surfactants, Surfactants Classified by HLB Numbers
{SNA} Biochemicals and Reagen
{SNA} Cell Culture, Detergents A to M, Detergents by Applications, Diagnostic Applications, Drug Delivery-Liposomes, Electrophoresis Chromatography, Enzymo

产品应用

非离子型表面活性剂。气相色谱固定液(最高使用温度140℃)，分离分析脂肪酸酯、醇、酮及卤化物。水溶性乳化剂。加溶剂。纺织工业用抗静电剂和纤维润滑剂。

安全信息

WGK Germany1

RTECSWG2933000

Personal Protective Equipment Eyeshields, Gloves

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Storage condition Store at room temperature, keep dry and cool {LY} Store at room temperature, keep dry and cool {} {LY} Store at room temperature, keep dry and cool {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature, keep dry and cool {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store

GHS Symbol

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 11,150,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >38400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,254,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   101,173,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1580 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,254,1974

其他信息

EPA化学物质信息:Sorbitan, monohexadecanoate, poly(oxy-1,2-ethanediyl) derivs.(9005-66-7)
所属类别二:化工助剂: 工业表面活性剂: 非离子表面活性剂
所属类别一:食品添加剂: 乳化剂、增稠剂和稳定剂
聚氧乙烯山梨糖醇酐单棕榈酸酯价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 30189428 吐温40;吐混40;聚氧乙烯山梨糖醇酐单棕榈酸酯;聚乙氧基棕榈酸清凉茶醇 500g 43元 2011/08/23 30189481 吐温40;吐混40;聚氧乙烯山梨糖醇酐单棕榈酸酯;聚乙氧基棕榈酸清凉茶醇 500ml 126.5元 2011/04/16 T0544 吐温40(=聚氧乙烯失水山梨醇单棕榈酸酯) Tween 40 (=Polyoxyethylene Sorbitan Monopalmitate) 25G 146元
所属类别三:食品添加剂: 乳化剂
图谱信息:聚氧乙烯山梨糖醇酐单棕榈酸酯(9005-66-7)红外图谱(IR2) 聚氧乙烯山梨糖醇酐单棕榈酸酯(9005-66-7)红外图谱(IR1)
参考质量标准二:FAO/WHO，1978 氧乙烯含量(以C2H4O计)/% 66.0～70.5 酸值 ≤2 水分/% ≤3 硫酸盐灰分/% ≤0.25 砷(以As计)/% ≤O.0003 重金属(PA Pb计)/% ≤0.001 皂化值 41～52 羟值 90~107
毒性:ADI 0～25mg/kg(FAO/WHO，2001)。有提高人体对流体石蜡和其他脂溶性物质吸收的能力。
毒害物质数据:9005-66-7(Hazardous Substances Data)
鉴别试验:溶解性溶于水、乙醇、甲醇、乙酸乙酯和丙酮；不溶于矿物油。按OT-42方法测定。均与“聚山梨酸酯 20(10024.)”中鉴别方法2、3相同。胶凝性配制60%(V/V)的试样混合液，在室温以下时应产生胶凝状物质。皂化100g试样经碱皂化后约可产生20g脂肪酸类和78g多元醇类。方法与“聚氧乙烯(8)硬脂酸酯(10021)”中鉴别方法5相同。
生产方法:在甲醇钠(或乙醇钠)的催化下，在：130~170℃：时在Span-40中通人一定量的环氧乙烷发生加成反应得产品。
用途:作O/W型食品乳化剂，单独使用或与司盘-60、司盘-65、司盘-80混合使用。我国规定可用于植物蛋白饮料，最大使用量为2.0g/kg。
使用限量:GB 2760-1996：同“10024，聚山梨酸酯20”。
参考质量标准一:FAO/WHO，1992 氧乙烯基团含量 66.0%～70.5% 相当于聚山梨酸酯40含量(以无水物计) 97.0%～103.0% 水分(GT-32-1) ≤3% 酸值(OT-4-1) ≤2 皂化值(OT-40-2；试样8g) 41～52 羟值(OT-26) 90～107 硫酸盐灰分(GT-5；试样5g) ≤0.25% 重金属(GT-16-2；试样2g) ≤10mg/kg 砷(GT-3) ≤3mg/kg
含量分析:按OT-36方法测定环氧乙烷含量。
浅黄色液体(放置后可能成凝胶状)。溶于水、甲醇、乙醇、异丙醇、乙二醇和棉子油，不溶于植物油及矿油。
RTECS号:WG2933000