PQ401 PQ401

CAS 196868-63-0 MFCD00160558

化学结构图

196868-63-0
SMILES: CC1=CC(NC(=O)NC2=CC(Cl)=CC=C2OC)=C2C=CC=CC2=N1

化学属性

Mol. FormulaC18H16ClN3O2
Mol. Weight341.79

别名和识别编码

Chemical NamePQ401
Synonym IGF-1R Inhibitor II IGF-1R Inhibitor II N-(5-Chloro-2-methoxyphenyl)-N'-(2-methylquinolin-4-yl)urea N-(5-Chloro-2-methoxyphenyl)-N′-(2-methylquinolin-4-yl)urea N-(5-Chloro-2-methoxyphenyl)-N'-(2-methylquinolin-4-yl)urea PQ401
CAS Number196868-63-0
PubChem Substance ID24724567
MDL NumberMFCD00160558
Chemical Name TranslationPQ401
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分类

  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Insulin-Like Growth Factor Receptor (IGF1R and IGf2R), Kinase/Phosphatase Biology, P, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors
  • {SNA} Bioactive Small Molecule Alphabetical Index, Insulin-Like Growth Factor Receptor (IGF1R and IGf2R), Kinase/Phosphatase Biology, PI-PZ, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Insulin-Like Growth Factor Receptor (IGF1R and IGf2R), Kinase/Phosphatase Biology, P,

相关文献及参考

  • Gable, K.L., et al., Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth. Mol. Cancer Ther. 5 , 1079-1086, (2006) 摘要

安全信息

GHS Symbol
WGK Germany3
Hazard Codes T
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Precautionary statements
  • P301+P310
Signal word Danger
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Receptor Tyrosine Kinase Biology - Kinase/Phosphatase Biology
  6. Receptor Tyrosine Kinase Inhibitors - Receptor Tyrosine Kinase Biology
  7. Insulin-Like Growth Factor Receptor (IGF1R and IGf2R) - Receptor Tyrosine Kinase Inhibitors

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