N,N-Dimethylsphingosine
CAS 119567-63-4 MFCD00153960
化学结构图
SMILES: CCCCCCCCCCCCC/C=C/[C@H](O)[C@@H](CO)N(C)C
化学属性
| Mol. Formula | C20H41NO2 |
|---|---|
| Mol. Weight | 327.545 |
别名和识别编码
| Chemical Name | N,N-Dimethylsphingosine |
|---|---|
| Synonym | (2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol D-Erythro-N,N-Dimethylsphingosine DMS Dimethylsphingosine N,N-Dimethylsphingosine (2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol N,N-Dimethyl-D-erythro-sphingosine N,N-Dimethylsphingenine |
| CAS Number | 119567-63-4 |
| MDL Number | MFCD00153960 |
| Chemical Name Translation |
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分类
- Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Lipids in Cell Signaling, New Products, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, Sphingolipids, Sphingosine Kinase (SK)
相关文献及参考
- Patti, G.J., et al., Metabolomics implicates alterd sphingolipids in chronic pain of neuropathic origin. Nature Chem. Biol. Jan. 22 , (2012)
- Spijkers, L.J., et al., FTY720 (Fingolimod) increases vascular tone and blood pressure in spontaneously hypertenisve rats via inhibition of sphingosine kinase. Br. J. Pharmacol. Jan. 17 , (2012)
- McDonald, R.A., et al., The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia. Br. J. Pharmacol. 159 , 543-553, (2010)
