CAS 826-39-1 MFCD00151462-Mecamylamine Hydrochloride 盐酸美加明 TAO{mole}

Mecamylamine Hydrochloride 盐酸美加明

CAS 826-39-1 MFCD00151462

化学结构图

SMILES: CNC1(C)[C@H]2CC[C@H](C2)C1(C)C.Cl

化学属性

Mol. Formula	C11H22ClN
Mol. Weight	203.75
Solubility	ethanol: 122 mg/mL

别名和识别编码

Chemical Name	Mecamylamine Hydrochloride
CAS Number	826-39-1
Synonym	2-(Methylamino)isocamphane hydrochloride, Inversine, N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride 2-(Methylamino)isocamphane hydrochloride Inversine N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride 2-(Methylamino)isocamphane hydrochloride; Inversine; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride 2-NORBORNANAMINE,N,2,3,3-TETRAMETHYL-,HYDROCHLORIDE 2-[METHYLAMINO]ISOCAMPHANE HYDROCHLORIDE 3-methylaminoisocamphanehydrochloride 3-methylaminoisokamfanchlorid Bicyclo2.2.1heptan-2-amine, N,2,3,3-tetramethyl-, hydrochloride MECAMYLAMINE MECAMYLAMINE USP MECAMYLAMINE HYDROCHLORIDE MECAMYLAMINE USP MecamycamineHydrochloride Mecamylamine (hydrochloride) {Chemicalbook} N,2 {} {SNA} Mecamylamine hydrochlor
MDL Number	MFCD00151462
EC Number	212-555-8
PubChem Substance ID	13221
Chemical Name Translation	盐酸美加明
Wiswesser Line Notation	L55 ATJ CM1 C1 D1 D1 &GH
InChI	InChI=1S/C11H21N.ClH/c1-10(2)8-5-6-9(7-8)11(10,3)12-4;/h8-9,12H,5-7H2,1-4H3;1H
Canonical SMILES	CC1(C)C(NC)(C)C2CCC1C2.[H]Cl

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产品应用

Nicotinic receptor antagonist; orally active ganglionic blocker. Antihypertensive.

安全信息

RTECSRB6900000

GHS Symbol

WGK Germany3

Precautionary statements

P301+P310
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

Signal word Danger

Hazard statements

H301 Toxic if swallowed 吞食有毒
H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

Hazard Codes Xn

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R22 Harmful if swallowed 吞咽有害

UN Number UN 2811 6.1/PG 3

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 177 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 117,169,1956

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New
   York, NY)  V.1-3, 1964-72.  Discontinued.  Volume(issue)/page/year:
   2,300,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 155 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 117,169,1956

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 63 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    19

Storage condition 2-8°C

其他信息

MOL 文件:826-39-1.mol
Sigma Aldrich:826-39-1(sigmaaldrich)