Ehna Hydrochloride 外消旋-9-(2-羟基-3-壬基)腺嘌呤盐酸盐
CAS 58337-38-5 MFCD00151066
化学结构图
SMILES:
化学属性
| Mol. Formula | C14H23N5O · HCl |
|---|---|
| Mol. Weight | 313.83 |
别名和识别编码
| Chemical Name | Ehna Hydrochloride |
|---|---|
| Synonym | erythro-9-Amino-β-hexyl-α-methyl-9H-purine-9-ethanol hydrochloride erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride erythro-9-Amino-β-hexyl-α-methyl-9H-purine-9-ethanol hydrochloride erythro-9-(2-Hydroxy-3-nonyl)adenine hydrochloride |
| MDL Number | MFCD00151066 |
| PubChem Substance ID | 24277713 |
| CAS Number | 58337-38-5 |
| Chemical Name Translation | 外消旋-9-(2-羟基-3-壬基)腺嘌呤盐酸盐 |
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分类
- {SNA} Adenosine
- {SNA} Adenosine Deaminase, Bioactive Small Molecule Alphabetical Index, E, Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism,
- {SNA} Adenosine Deaminase, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, E, Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism
- {SNA} Adenosine Deaminase,
- {SNA} Adenosine Deaminase, Bioactive Small Molecule Alphabetical Index, E, Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, 生物活性小分子, 细胞信号转导和神经科学,
相关文献及参考
- [2]. Michie AM, et al. Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.Cell Signal. 1996 Feb;8(2):97-110.
- [3]. Blázquez-Bermejo C, et al. Increased dNTP pools rescue mtDNA depletion in human POLG-deficient fibroblasts. FASEB J. 2019 Jun;33(6):7168-7179.
- Muraoka, T., et al., Automated enzymatic measurement of adenosine deaminase isoenzyme activities in serum. Anal. Biochem. 187 , 268-272, (1990) 摘要
- Schaeffer, HJ, and Schwender, CF, Enzyme inhibitors. 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl) adenines. J. Med. Chem. 17 , 6-8, (1974) 摘要
- [1]. Podzuweit T, et al. Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine.Cell Signal.
