Uridine 5'-(trihydrogen diphosphate), disodium salt 尿苷-5'-二磷酸二钠盐
CAS 27821-45-0 MFCD00149253
化学结构图
SMILES: O.[Na+].[Na+].[O-]P(O)(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O
化学属性
| Mol. Formula | C9H12N2Na2O12P2· xH2O |
|---|---|
| Mol. Weight | 448.12 (anhydrous basis) |
别名和识别编码
| Chemical Name | Uridine 5'-(trihydrogen diphosphate), disodium salt |
|---|---|
| Synonym | 尿苷-5'-二磷酸 尿苷-5′-二磷酸 二钠盐 水合物 5'-UDP-Na2 |
| MDL Number | MFCD00149253 |
| PubChem Substance ID | 57653599 |
| Beilstein Registry Number | 8817400 |
| EC Number | 248-678-9 |
| CAS Number | 27821-45-0 |
| Chemical Name Translation | 尿苷-5'-二磷酸二钠盐 |
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分类
- {SNA} Nucleotides, 核苷，核苷酸和寡核苷酸, 生化试剂
- {SNA} Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotides
相关文献及参考
- [2]. Kim B, et al. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J Immunol. 2011 Mar 15;186(6):3701-9.
- [3]. Edyta Gendaszewska-Darmach, et al. Nucleoside 5'-O-monophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation. Oncotarget. 2016 Oct 25;7(43):69358-69370.
- [4]. Zainab S B Abbas, et al. UDP-sugars activate P2Y 14 receptors to mediate vasoconstriction of the porcine coronary artery. Vascul Pharmacol. 2018 Apr;103-105:36-46.
- [1]. Jacobson KA, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 2009 Mar;5(1):75-89.
- [1]. Jacobson KA, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 2009 Mar;5(1):75-89.
- [2]. Kim B, et al. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J Immuno
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
