CAS 32449-92-6 MFCD00135622-D-Glucurone 葡醛内酯 TAO{mole}

D-Glucurone 葡醛内酯

CAS 32449-92-6 MFCD00135622

化学结构图

SMILES: O=C1O[C@@H]([C@H](O)CO)[C@@H](O)[C@H]1O

化学属性

Mol. Formula	C6H8O6
Mol. Weight	176
Melting Point	170-176
TSCA	Yes
Density	1.749

别名和识别编码

Chemical Name	D-Glucurone
CAS Number	32449-92-6
Synonym	D-Glucuronic Acid Lactone D-Glucuronic acid lactone D-Glucuronolactone D-葡萄糖醛酸内酯 Glucurolactone Glucurone Glucurono-6,3-lactone Glycurone 呋喃糖醛酸γ-内酯
MDL Number	MFCD00135622
PubChem Substance ID	87570270
Beilstein Registry Number	83595
EC Number	251-053-3
Merck Number	4467
Reaxys-RN	1284779
Chemical Name Translation	葡醛内酯
Wiswesser Line Notation	T55 BOV FOTJ DQ GQ HQ

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产品应用

该品为解毒剂。能与肝内和肠内的毒物结合成无毒的葡萄糖醛酸结合物，并排出体外，有保肝和解毒作用。用于肝炎、肝硬化、食物或药物中毒。

安全信息

WGK Germany2

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RTECSLZ8930000

Signal word Warning

GHS Symbol

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,2

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 940 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,225,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 4700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,225,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 4700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,225,1982