(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-methylpiperidine-3,4,5-triol
CAS 69567-10-8 MFCD00133609
化学结构图
SMILES: CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
化学属性
| Mol. Formula | C7H15NO4 |
|---|---|
| Mol. Weight | 177.20 |
别名和识别编码
| Chemical Name | N-Methyl-1-deoxynojirimycin |
|---|---|
| CAS Number | 69567-10-8 |
| Synonym | N-Methyl-1-deoxynojirimycin 1,5-Dideoxy-1,5-imino-1-methyl-D-sorbitol (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-methyl-3,4,5-piperidinetriol N-Methylmoranolin |
| MDL Number | MFCD00133609 |
| PubChem Substance ID | 24896690 |
| Beilstein Registry Number | 1524564 |
| Alfabeta Name | HYDROXYMETHYLMETHYLPIPERIDINETRIOL RRRS234521345(())------,,,,, |
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分类
- {SA} Antibiotics, Antibiotics A to Z, Antibiotic
- Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antiviral, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Chemical Structure Class, D to K, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Glucosamines, Glucosidase I, Glycobiology, Inhibitors, Inhibitors and Substrates, Inhibits an Enzyme, M, Mechanism of Action, Post-Translational Modification, Proteomics, Spectrum of Activity
- {SNA} Antibiotics A to Z,
产品应用
- Interfers with the normal processing of N-linked glycoproteins by inhibiting the action of glucosidases that remove glycosyl residues from Glc3Man9GlcNAc2 following the addition of this moiety to a n
相关文献及参考
- [2]. Arai M, et al. Role of protein kinase C in the reduction of infarct size by N-methyl-1-deoxynojirimycin, an alpha-1,6-glucosidase inhibitor. Br J Pharmacol. 2001 Jul;133(5):635-42.
- [3]. Nishida Y, et al. N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly improves postischemic left ventricular dysfunction. Heart Vessels. 2000;15(6):268-73.
- Bause, E., et al. FEBS Lett. 206 , 208, (1986)
- Beil. 21 ,V,6,−1
- Biochem. J., 226, 733 (1985),
- Biochem. J., 238, 335 (1986),
- Carbohydrate Res., 151, 21 (1986),
- FEBS Letts., 183, 29 (1985),
- Trudel, G.C., and Holland, P.C. Biochem. Cell Biol. 68 , 1411, (1990) 摘要
- [1]. Arai M, et al. N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, mar
- [1]. Arai M, et al. N-methyl-1-deoxynojirimycin (MOR-14), an alpha-glucosidase inhibitor, markedly reduced infarct size in rabbit hearts. Circulation. 1998 Apr 7;97(13):1290-7.
