MAGAININ 1
CAS 108433-99-4 MFCD00133521
化学结构图
SMILES: CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(O)=O
化学属性
| Mol. Formula | C112H177N29O28S |
|---|---|
| Mol. Weight | 2409.85 |
别名和识别编码
| Chemical Name | Magainin I |
|---|---|
| MDL Number | MFCD00133521 |
| CAS Number | 108433-99-4 |
| Synonym | |
| Chemical Name Translation |
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分类
- {SNA} Antibacterial, Antibiotic Peptides,
- {SNA} Antibacterial, Antibiotic Peptides, Antibiotics A to Z, Antibiotics G-M, Antifungal, Antiviral, Chemical Structure Class, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators, Immunomodulators and Antibiotics, Interferes with Cell Membrane Permeability (Ionophores), L - Z, Mechanism of Action, Peptides, Peptides and Proteins, Peptides for Cell Biology, Spectrum of Activity, 抗生素, 生化试剂, 细胞信号转导和神经科学, 细胞生物学
- Antibacterial, Antibiotic Peptides, Antibiotic
相关文献及参考
- Zasloff, M. Proc. Natl. Acad. Sci. U. S. A. 84 , 5449, (1987) 摘要
- Giovannini, M.G., et al. Biochem. J. 243 , 113, (1987) 摘要
- Vorland, L.H., et al., Initial binding sites of antimicrobial peptides in Staphylococcus aureus and Escherichia coli. Scand. J. Infect. Dis. 31 , 467-473, (1999) 摘要
- Huang, H., Action of antimicrobial peptides: Two-state model. Biochemistry 39 , 8347, (2000) 摘要
- Wieprecht, T., Binding of antibacterial magainin peptides to electrically neutral membranes: thermodynamics and structure. Biochemistry 38 , 10377, (1999) 摘要
- Helmerhorst, E.J., A critical comparison of the hemolytic and fungicidal activities of cationic antimicrobial peptides. FEBS Lett. 449 , 105, (1999) 摘要
- Matsuzaki K., Magainins as paradigm for the mode of action of pore forming polypeptides. Biochim. Biophys. Acta 1376 , 391-400, (1998) 摘要
