β-Estradiol-Water Soluble
CAS N/A MFCD00133134
化学结构图
SMILES: C[C@H]1[C@@H]2O[C@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O[C@H]5O[C@H](CO)[C@@H](O[C@H]6O[C@H](CO)[C@@H](O[C@H]7O[C@H](CO)[C@@H](O[C@H]8O[C@H](CO)[C@@H](O[C@@H](O[C@@H]2CO)[C@@H]1O)[C@H](O)[C@H]8O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4OCCCO)[C@H](O)[C@H]3O.C[C@]12CC[C@H]3[C@@H](CCC4C=C(O)C=CC=43)[C@@H]1CC[C@@H]2O
化学属性
| Mol. Formula | C46H78O35.C18H24O2 |
|---|---|
| Mol. Weight | 1463.47 |
别名和识别编码
| Chemical Name | β-Estradiol-Water Soluble |
|---|---|
| Synonym | Cyclodextrin-encapsulated 17β-estradiol Cyclodextrin-encapsulated 17β-estradiol |
| MDL Number | MFCD00133134 |
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分类
- Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Estrogen, Hormones, Reagents and Supplements, Steroid Hormones
- {SNA} Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Estrogen, Hormones, Reagents and Supplements, Steroid Hormones
- {SNA} Cytokines, Growth Factors and Hormones, Estrogen, Hormones, Steroid Hormones, 细胞信号转导和神经科学, 细胞培养, 细胞生物学, 试剂和添加剂
相关文献及参考
- Akama, K.T., and Mcewen, B.S., Estrogen Stimulates Postsynaptic Density-95 Rapid Protein Synthesis via the Akt/Protein Kinase B Pathway J. Neurosci. 23 , 2333-9, (2003) 摘要
- Escribese, M.M., et al., Estrogen inhibits dendritic cell maturation to RNA viruses Blood 112 , 4574-84, (2008) 摘要
- Osako, M.K., et al., Estrogen Inhibits Vascular Calcification via Vascular RANKL System. Common Mechanism of Osteoporosis and Vascular Calcification Circ. Res. 107 , 466-475, (2010) 摘要
安全信息
GHS Symbol
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P263 Avoid contact during pregnancy/while nursing. 怀孕/哺乳期间避免接触。
- P308+P313
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P273 Avoid release to the environment. 避免释放到环境中。
- H350 May cause cancer 可能致癌
- H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
- H340 May cause genetic defects 可能导致遗传性缺陷
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
- R60 May impair fertility 可能降低生殖能力
- R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
- R64 May cause harm to breast-fed babies 可能导致伤害脯乳期婴儿
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
