Proteinase, bacterial 蛋白酶，细菌

CAS 9014-01-1 MFCD00132092

化学结构图

9014-01-1
SMILES:

化学属性

Mol. Weight1.01
Mol. Formula
Density1.16
Appearance amber liq. (semitransparent) brown liq. off-white granulate
Stabilitystore cold

别名和识别编码

Synonym Nagarse Subtilopeptidase A E.C. 3.4.4.16 SP 266 Subtilisin carlsburg Subtilisin NOVO Everlase 16.0 L Subtilopeptidase B Subtilisin bpn' Neutrase® 0.8L Savinase® 16.0L Bioprase Proteinase 来源于地衣芽孢杆菌 Subtilisin A Subtilisin Carslberg Alkaline Protease Proteinase from Bacillus licheniformis Subtilo peptidase A 蛋白酶 来源于地衣芽孢杆菌 ALK-enzyme Alcalase® 2.4L Proteinase 来源于地衣芽孢杆菌 Subtilisin A Subtilisin Carslberg Subtilopeptidase C 蛋白酶 来源于解淀粉芽胞杆菌 Thermoase PC-10 Molsin Esperase® 8.0L S Alcalase Subtilisin Actinase E Pronase E Bacillopeptidase A Subtilopeptidase bpn'
MDL NumberMFCD00132092
CAS Number9014-01-1
EC Number232-752-2
Chemical NameProteinase, bacterial
Chemical Name Translation蛋白酶，细菌
PubChem Substance ID87574717
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分类

  • {SNA} 3.4.x.x Peptidases, 3.x.x.x Hydrolases, Application Index, Biochemicals and Reagents, Enzyme Class Ind
  • {SNA} 3.4.x.x Peptidases, 3.x.x.x Hydrolases, Analytical and Industrial Enzymes, Application Index, Biochemicals and Reagents, Core Bioreagents, Enzyme Class Index, Enzymes, Enzymes, Inhibitors, and Substrates, General Reagents, Life Science Reagents for Protein Expression and Purification, Proteases, Proteases & Protein Sequencing, Proteases for Mitochondrial Isolation, Proteolytic Enzymes and Substrates, Research Essentials, Subtilisin
  • {SNA} Additional Reagents, Application Index, Biochemicals and Reagents,
  • {SNA} 3.4.x.x Peptid

相关文献及参考

  • Guntelberg, A.V. and Ottesen, M. Comp. rend. Trav. Lab. Carlsberg 29 , 36, (1954)
  • Benton, C.R., et al., Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria. J. Phys. Chem. 586 , 1755-66, (2008) 摘要
  • Singh, A., et al., Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels. Proc. Natl. Acad. Sci. U. S. A. 106 , 13100-5, (2009) 摘要

安全信息

RTECSCO9550000
GHS Symbol
Precautionary statements
  • P342+P311
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H318 Causes serious eye damage 严重伤害眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H302 Harmful if swallowed 吞食有害
WGK Germany1
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Hazard Codes 9
Safety Statements
  • S24 Avoid contact with skin 避免皮肤接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S22 Do not breathe dust 不要吸入粉尘；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
Risk Statements
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R50 Very toxic to aquatic organisms 对水生生物极毒
  • R22 Harmful if swallowed 吞咽有害
Storage condition 0-10 储存温度 2-8°C 0-10°C
UN Number
Packing GroupIII 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 7,581,1969

其他信息

  • Neutral protease (Dispase®) is a non-mammalian animal origin free (AOF) metallo, neutral protease, purified by methods developed at Aladdin. Its mild proteolytic action makes the enzyme especially suitable for the preparation of primary cells and secondary (subcultivation) cell culture, since it is gentle on cell membranes. This protease is also used as a secondary enzyme in cell isolation and tissue dissociation applications, commonly used with collagense.

系列性分类

  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Life Science Reagents for Immunohistochemistry (IHC) - Core Bioreagents
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Analytical Enzymes - Enzymes, Inhibitors, and Substrates
  5. Novozymes: Quality Environmentally-Friendly Enzymes - Analytical Enzymes
  1. Life Science 生命科学
  2. Molecular Biology 分子生物学
  3. Molecular Biology Enzymes - Molecular Biology
  4. Modifying Enzymes - Molecular Biology Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Proteolytic Enzymes and Substrates - Enzymes, Inhibitors, and Substrates
  5. Proteolytic Enzymes - Proteolytic Enzymes and Substrates
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Immune Cell Signaling and Blood - Cell Signaling and Neuroscience
  5. Immune System Regulation - Immune Cell Signaling and Blood
  6. AIDS and Viral Research Reagents - Immune System Regulation
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Proteases & Protein Sequencing - Application Index
  6. Proteases - Proteases & Protein Sequencing
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Class Index - Enzymes, Inhibitors, and Substrates
  5. 3.x.x.x Hydrolases - Enzyme Class Index
  6. 3.4.x.x Peptidases - 3.x.x.x Hydrolases
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Post-Translational Modification - Proteomics
  4. Glycobiology - Post-Translational Modification
  5. Carbohydrate-active Enzymes - Glycobiology
  6. GPI Anchor Enzymes - Carbohydrate-active Enzymes
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Application Index - Enzymes, Inhibitors, and Substrates
  5. Molecular Biology Tested - Application Index
  6. Protein and Nucleic Acid Isolation - Molecular Biology Tested
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Proteolytic Enzymes and Substrates - Enzymes, Inhibitors, and Substrates
  5. Selective Proteolytic Enzymes - Proteolytic Enzymes and Substrates
  6. Pronase E - Selective Proteolytic Enzymes
  1. Life Science 生命科学
  2. Plant Biotechnology 植物生物技术
  3. Plant Proteomics - Plant Biotechnology
  4. Protein Identification - Plant Proteomics
  5. Protein Digest - Protein Identification
  1. Life Science 生命科学
  2. Proteomics 蛋白质组学
  3. Mass Spectrometry - Proteomics
  4. Enzymatic and Chemical Protein Cleavage - Mass Spectrometry
  5. Proteases for Cleavage of Proteins - Enzymatic and Chemical Protein Cleavage
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Analytical Enzymes - Enzymes, Inhibitors, and Substrates
  5. Subtilisin - Analytical Enzymes
  6. Enzymes - Subtilisin
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Analytical Enzymes - Enzymes, Inhibitors, and Substrates
  5. Subtilisin - Analytical Enzymes
  6. Enzymes - Subtilisin
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Proteolytic Enzymes and Substrates - Enzymes, Inhibitors, and Substrates
  5. Selective Proteolytic Enzymes - Proteolytic Enzymes and Substrates
  6. Subtilisin - Selective Proteolytic Enzymes
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Enzyme
  1. Biocatalyst
  2. Biocatalysts
  1. Catalysts
  2. Biocatalysts
  1. Biocatalyst
  2. 96-0224 Novozymes Endoprotease Screening Kit (contains 6 endoprotease enzymes)
  1. Catalysts
  2. 96-0224 Novozymes Endoprotease Screening Kit (contains 6 endoprotease enzymes)

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