Toxins, pertussis

CAS 70323-44-3 MFCD00131841

化学结构图

70323-44-3
SMILES:

别名和识别编码

Synonym Pertussigen Histamine-sensitizing factor Lymphocytosis-promoting factor Pertussis toxin from Bordetella pertussis IAP Islet activating protein
MDL NumberMFCD00131841
Chemical NameToxins, pertussis
CAS Number70323-44-3
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分类

  • {SNA} Bacteria, Bacteria-derived adjuvants, Bioactive Small Molecules, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, G Protein Function, G Proteins and Cyclic Nucleotides, P, Reagents, Toxins and Venoms, Vaccine Adjuvants, Vaccine Production

安全信息

GHS Symbol
WGK Germany2
Precautionary statements
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H330 Fatal if inhaled 吸入致命
  • H302 Harmful if swallowed 吞食有害
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSXW5883750
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 127 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TJEMAO Tohoku Journal of Experimental Medicine.  (Maruzen Co. Ltd., Export
   Dept., P.O. Box 5050, Tokyo Int., 100-31 Tokyo, Japan)  V.1-    1920-
   Volume(issue)/page/year: 130,105,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17160 ng/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INFIBR Infection and Immunity.  (American Soc. for Microbiology, 1913 I St.,
   NW, Washington, DC 20006)  V.1-    1970-  Volume(issue)/page/year:
   31,495,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 114 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TJEMAO Tohoku Journal of Experimental Medicine.  (Maruzen Co. Ltd., Export
   Dept., P.O. Box 5050, Tokyo Int., 100-31 Tokyo, Japan)  V.1-    1920-
   Volume(issue)/page/year: 130,105,1980

系列性分类


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