Nuclease micrococcal from Staphylococcus aureus微球菌核酸酶 微球菌核酸酶
CAS 9013-53-0 MFCD00131731
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别名和识别编码
| MDL Number | MFCD00131731 |
|---|---|
| CAS Number | 9013-53-0 |
| Synonym | Endonuclease micrococcal Endonuclease micrococcal MNase Micrococcal endonuclease Endonuclease micrococcal MNase Micrococcal endonuclease Micrococcal nuclease MNase Micrococcal endonuclease Micrococcal nuclease Nuclease micrococcal from Staphylococcus aureus |
| EC Number | 232-748-0 |
| Chemical Name | Nuclease micrococcal from Staphylococcus aureus微球菌核酸酶 |
| Chemical Name Translation | 微球菌核酸酶 |
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分类
- {SNA} 3.1.x.x Acting on esters,
- {SNA} 3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Application Index, Biochemicals and Reagents, Enzyme Class Index, Enzymes for Diagnostic Kit Manufacturing, Enzymes, Inhibitors, and Substrates, General Metabolic Enzymes, Molecular Diagnostics, Nucleotide Metabolism, Protein & Nucleic Acid Isolation, 代谢组学, 细胞生物学
- {SNA} 3.1.x.x Acting on esters, 3.x.x.x Hydrolases, Application Index, Enzyme Class Index, Enzymes for Diagnostic Kit Manufacturing, General Metabolic Enzymes, Molecular Diagnostics, Nucleotide Metabolism, Protein & Nucleic Acid Isolation, 代谢组学,
- {SNA} 3.1.x.x Acting on esters,
产品应用
- Nuclease from Staphylococcus aureus has been used in a study to assess coagulase and heat-resistant strains found in animals. It has also been used in a study to investigate the expression characteristic of two genes in S. aureus that encode two thermostable nucleases.
安全信息
其他信息
- Micrococcal nuclease catalyzes cleavage of both DNA and RNA to yield 3'-nucleotides. It exhibits exo- and endo-5'-phosphodiesterase activities. The enzyme catalyzes preferential endohydrolysis of the RNA and DNA at sites rich in adenylate or uridylate and deoxyadenylate or thymidylate. The enzyme has a molecular weight of 16,807 daltons and is calcium dependent. The pH optimum is 9.2 but varies depending upon the concentration of ionized calcium present.
