Lysozyme chloride [JAN] 溶菌酶 氯化物形式 来源于鸡蛋白

CAS 9066-59-5 MFCD00131557

化学结构图

9066-59-5
SMILES:

别名和识别编码

Synonym 溶菌酶 来源于鸡蛋白 粘肽 N-乙酰胞壁质水解酶 胞壁质酶 Mucopeptide N-acetylmuramoylhydrolase 胞壁质酶 溶菌酶 来源于人类中性粒细胞 溶菌酶 溶菌酶 人 Lysobac™ r Lysozyme Mucopeptide N-acetylmuramoylhydrolase 胞壁质酶 粘肽 N-乙酰胞壁质水解酶 胞壁质酶 溶菌酶 氯化物形式 来源于鸡蛋白
MDL NumberMFCD00131557
CAS Number12650-88-3
EC Number232-954-0
Chemical NameLysozyme chloride form from chicken egg white
Chemical Name Translation溶菌酶 氯化物形式 来源于鸡蛋白
InChIKeyVEXZGXHMUGYJMC-UHFFFAOYSA-N
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分类

  • {SA} 3.2.x.x Glycosidases, 3.x.x.x Hydrolases, Application Index, Biochemicals and Reagents, Carbohydrate Hydrolysis, Carbohydrate and PTM Analysis, Carbohydrate hydrolysis & PTM analysis, Enzyme Class Index, Enzymes, Inhibitors, and Substrates
  • {SNA} 3.2.x.x Glycosidases, 3.x.x.x Hydrolases, Amino Acid, Peptide & Protein Standards, Analytical Standards, Enzyme Class Index, Proteins / Enzymes Standards, 分析/色谱, 生化试剂, 酶、抑制剂和底物
  • {SNA} 3.2.x.x Glycosidases, 3.x.x.x Hydrolases, Application Index, Bacterial, Carbohydrate Hydrolysis, Carbohydrate and PTM Analysis, Ca

产品应用

  • 酶分解细菌的细胞壁;用于制备原生质球。

相关文献及参考

  • Shugar, D. Biochim. Biophys. Acta 8 , 302, (1952) 摘要
  • Hedtjärn, M. et al, Inflammatory Gene Profiling in the Developing Mouse Brain After Hypoxia-Ischemia J. Cereb. Blood Flow Metab. 24 , 1333-1351, (2004) 摘要
  • Merck 14 ,5640

安全信息

Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany2
RTECSFJ5959000 OL5989000 OL5989000
Hazard Codes B
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Storage condition 储存温度2-8℃
GHS Symbol
Precautionary statements
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5800 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 21,587,1981

其他信息

  • Lysozyme preferentially hydrolyzes the β-1,4 glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. A slightly more limited activity is exhibited toward chitin oligomers. It has a molecular weight of 14,388 daltons. Optimum pH is 9.2. Lysozyme is inhibited by surface active agents such as dodecyl sulfate, alcohol and fatty acids. Imidazole and indole derivatives form inhibitory charged transfer complexes.

系列性分类


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